Thomas Donner
Overview
Explore the profile of Thomas Donner including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
451
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0
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Recent Articles
1.
Majety N, Ahmed R, Al-Hallaf R, Paul P, Giwa A, Heinemann J, et al.
Immunol Invest
. 2024 Sep;
53(7):1125-1140.
PMID: 39268869
Introduction: Dual-expressing lymphocytes (DEs) are unique immune cells that express both B cell receptors (BCRs, surface antibody) and T cell receptors (TCRs). In type 1 diabetes, DE antibodies are predominated...
2.
Gavigan C, Donner T
J Diabetes Res
. 2023 Aug;
2023:9972132.
PMID: 37589043
Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are potent antihyperglycemic agents with beneficial effects on weight, cardiovascular, and renal outcomes. Physicians lack guidance as to which patients with insulin-requiring type...
3.
Ahmed R, Omidian Z, Giwa A, Donner T, Jie C, Hamad A
Cell
. 2021 Feb;
184(3):840-843.
PMID: 33545037
We have recently identified a novel lymphocyte that is a dual expresser (DE) of TCRαβ and BCR. DEs in T1D patients are predominated by a public BCR clonotype (clone-x) that...
4.
Giwa A, Ahmed R, Omidian Z, Majety N, Karakus K, Omer S, et al.
World J Diabetes
. 2020 Jan;
11(1):13-25.
PMID: 31938470
Type 1 diabetes (T1D) is an autoimmune disease that usually strikes early in life, but can affect individuals at almost any age. It is caused by autoreactive T cells that...
5.
Ahmed R, Omidian Z, Giwa A, Cornwell B, Majety N, Bell D, et al.
Cell
. 2019 Jun;
177(6):1583-1599.e16.
PMID: 31150624
T and B cells are the two known lineages of adaptive immune cells. Here, we describe a previously unknown lymphocyte that is a dual expresser (DE) of TCR and BCR...
6.
Omidian Z, Ahmed R, Giwa A, Donner T, Hamad A
Cell Immunol
. 2019 Feb;
339:33-40.
PMID: 30765202
Interleukin-17 (IL-17) is a potent proinflammatory cytokine that protects a host against fungal and extracellular bacterial infections. On the other hand, excessive or dysregulated production of IL-17 underlines susceptibility to...
7.
Ahmed R, Omidian Z, Donner T, Hamad A
Discov Med
. 2018 Nov;
26(142):79-83.
PMID: 30399325
CD5+ B cells expand in many autoimmune diseases, including type 1 diabetes (T1D), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE). Furthermore, CD5+ B cells contain important subsets: IL-10-producing B-reg...
8.
Giwa A, Ahmed R, Donner T, Yagita H, Hamad A
Front Immunol
. 2017 Dec;
8:1584.
PMID: 29218044
No abstract available.
9.
Hamad A, Ahmed R, Donner T, Fousteri G
Discov Med
. 2016 Apr;
21(115):213-9.
PMID: 27115172
Immunotherapy has revolutionized treatment of cancers and autoimmune diseases. Bucking the trend, however, is type 1 diabetes (T1D), although it is one of best understood autoimmune diseases and individuals at...
10.
Saxena A, Khosraviani S, Noel S, Mohan D, Donner T, Hamad A
Cytokine
. 2014 Dec;
74(1):27-34.
PMID: 25481648
Interleukin-10 (IL-10) is arguably the most potent anti-inflammatory cytokine. It is produced by almost all the innate and adaptive immune cells. These cells also serve as its targets, indicating that...