Thomas Damgaard Sandahl
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Explore the profile of Thomas Damgaard Sandahl including associated specialties, affiliations and a list of published articles.
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54
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558
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Recent Articles
1.
Hovden Christensen S, Teicher Kirk F, Gyldenholm T, Munk E, Eilersen Hjerrild B, Kvistgaard H, et al.
Clin Chim Acta
. 2024 Sep;
565:119978.
PMID: 39332658
Wilson disease (WD) is a rare genetic disorder characterized by copper overload, primarily affecting the liver and brain, and the organ damage is believed to be caused by non-ceruloplasmin-bound copper...
2.
Hansen B, Vandriel S, Vig P, Garner W, Mogul D, Loomes K, et al.
Hepatology
. 2023 Dec;
79(6):1279-1292.
PMID: 38146932
Background And Aims: Alagille syndrome (ALGS) is characterized by chronic cholestasis with associated pruritus and extrahepatic anomalies. Maralixibat, an ileal bile acid transporter inhibitor, is an approved pharmacologic therapy for...
3.
Teicher Kirk F, Munk D, Swenson E, Quicquaro A, Holm Vendelbo M, Schilsky M, et al.
Hepatology
. 2023 Dec;
79(5):1065-1074.
PMID: 38088886
Background And Aims: Trientine (TRI) and D-penicillamine (PEN) are used to treat copper overload in Wilson disease. Their main mode of action is thought to be through the facilitation of...
4.
Teicher Kirk F, Munk D, Swenson E, Quicquaro A, Holm Vendelbo M, Larsen A, et al.
J Hepatol
. 2023 Dec;
80(4):586-595.
PMID: 38081365
Background & Aims: In Wilson disease (WD), copper accumulates in the liver and brain causing disease. Bis-choline tetrathiomolybdate (TTM) is a potent copper chelator that may be associated with a...
5.
Munk D, Holm Vendelbo M, Teicher Kirk F, Rewitz K, Bender D, Vase K, et al.
JHEP Rep
. 2023 Oct;
5(11):100916.
PMID: 37886434
Background & Aims: In Wilson disease (WD), copper accumulation and increased non-ceruloplasmin-bound copper in plasma lead to liver and brain pathology. To better understand the fate of non-ceruloplasmin-bound copper, we...
6.
Munk D, Teicher Kirk F, Vendelbo M, Vase K, Munk O, Ott P, et al.
J Vis Exp
. 2023 May;
(194).
PMID: 37184248
Copper is an essential trace element, functioning in catalysis and signaling in biological systems. Radiolabeled copper has been used for decades in studying basic human and animal copper metabolism and...
7.
Einer C, Munk D, Park E, Akdogan B, Nagel J, Lichtmannegger J, et al.
Gastroenterology
. 2023 Mar;
165(1):187-200.e7.
PMID: 36966941
Background & Aims: Excess copper causes hepatocyte death in hereditary Wilson's disease (WD). Current WD treatments by copper-binding chelators may gradually reduce copper overload; they fail, however, to bring hepatic...
8.
Codoni G, Kirchner T, Engel B, Villamil A, Efe C, Stattermayer A, et al.
JHEP Rep
. 2022 Nov;
5(1):100605.
PMID: 36440259
Background & Aims: Liver injury with autoimmune features after vaccination against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is increasingly reported. We investigated a large international cohort of individuals...
9.
Sandahl T, Medici V
Mol Ther Methods Clin Dev
. 2022 Nov;
27:293-294.
PMID: 36320415
No abstract available.
10.
Laursen T, Bossen L, Pihl R, Troldborg A, Sandahl T, Hansen A, et al.
J Clin Transl Hepatol
. 2022 Oct;
10(5):796-802.
PMID: 36304505
Background And Aims: There is an unmet need for new biomarkers to improve diagnostics and prognostics in primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). Inter-α-inhibitor heavy chain 4...