Thomas Coyne
Overview
Explore the profile of Thomas Coyne including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
180
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0
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Recent Articles
1.
Carson K, Newsome S, Kim E, Wagner-Johnston N, Geldern G, Moskowitz C, et al.
Cancer
. 2014 Apr;
120(16):2464-71.
PMID: 24771533
Background: Brentuximab vedotin (BV) is an anti-CD30 monoclonal antibody-drug conjugate that was approved in 2011 for the treatment of patients with anaplastic large cell and Hodgkin lymphomas. The product label...
2.
Algharras A, Mamourian A, Coyne T, Mohan S
J Clin Diagn Res
. 2014 Feb;
7(12):3020-2.
PMID: 24551717
Acute myeloid leukemia (AML) is a hematologic malignancy that can present with central nervous system (CNS) symptoms. Neurological symptoms may result from the local accumulation of malignant cells in or...
3.
Venneti S, Felicella M, Coyne T, Phillips J, Gorovets D, Huse J, et al.
J Neuropathol Exp Neurol
. 2013 Mar;
72(4):298-306.
PMID: 23481705
Trimethylation of histone 3 lysine 9 (H3K9me3) is a marker of repressed transcription. Cells transfected with mutant isocitrate dehydrogenase (IDH) show increased methylation of histone lysine residues, including H3K9me3, because...
4.
Alsheik E, Coyne T, Hawes S, Merikhi L, Naples S, Kanagarajan N, et al.
Gastroenterol Res Pract
. 2011 Oct;
2012:947694.
PMID: 21960998
Background. The prevalence of fecal incontinence varies tremendously as a result of inadequate data collection methods. Few office-based studies have assessed the prevalence of fecal incontinence and none have looked...
5.
Rhodes R, Monastersky B, Tyagi R, Coyne T
J Neurol Sci
. 2011 Aug;
309(1-2):18-25.
PMID: 21840544
A 73-year-old man had episodic encephalopathy, ataxia and neuropathy. Symptoms largely resolved but adenopathy later lead to the diagnosis of a low-grade follicular lymphoma. The neurological symptoms soon recurred with...
6.
Woodbury D, Len G, Reynolds K, Geoffrey McAuliffe W, Coyne T, Wu K
Cytotechnology
. 2008 Dec;
58(2):77-84.
PMID: 19052892
Stem cells have received significant attention for their envisioned potential to treat currently unapproachable diseases. No less important is the utility of stem cells to serve as model systems of...
7.
Mitchell S, Ellingson C, Coyne T, Hall L, Neill M, Christian N, et al.
Hum Mutat
. 2008 Jul;
30(1):56-60.
PMID: 18666241
The urea cycle is the primary means of nitrogen metabolism in humans and other ureotelic organisms. There are five key enzymes in the urea cycle: carbamoyl-phosphate synthetase 1 (CPS1), ornithine...
8.
Gundry C, Dobrowolski S, Martin Y, Robbins T, Nay L, Boyd N, et al.
Nucleic Acids Res
. 2008 May;
36(10):3401-8.
PMID: 18448472
Genotyping by high-resolution melting analysis of small amplicons is homogeneous and simple. However, this approach can be limited by physical and chemical components of the system that contribute to intersample...
9.
Dobrowolski S, Ellingson C, Coyne T, Grey J, Martin R, Naylor E, et al.
Mol Genet Metab
. 2007 May;
91(3):218-27.
PMID: 17502162
Phenylketonuria (PKU, MIM 261600; EC 1.14.16.1) results from mutations in the phenylalanine hydroxylase (PAH) gene. Newborn metabolic disease screening uses blood dried on filter paper (DBS) to prospectively identify candidate...