Thomas Brinker
Overview
Explore the profile of Thomas Brinker including associated specialties, affiliations and a list of published articles.
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30
Citations
1069
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Recent Articles
1.
Klinge P, Leary O, Allen P, Svokos K, Sullivan P, Brinker T, et al.
J Neurosurg Spine
. 2024 Mar;
40(6):758-766.
PMID: 38489815
Objective: Tethered cord syndrome (TCS) comprises three symptom categories: back/leg pain, bowel/bladder, and neurological complaints. MRI typically reveals a low-lying conus medullaris, filum terminale (FT) pathology, or lumbosacral abnormalities. FT...
2.
Klinge P, Ma K, Leary O, Sastry R, Sayied S, Venegas O, et al.
Sci Rep
. 2023 Mar;
13(1):5111.
PMID: 36991111
A series of epidemiological studies have shown the limited life expectancy of patients suffering from idiopathic normal pressure hydrocephalus (iNPH). In most cases, comorbid medical conditions are the cause of...
3.
Klinge P, McElroy A, Leary O, Donahue J, Mumford A, Brinker T, et al.
Neurosurgery
. 2022 Jul;
91(4):618-624.
PMID: 35852974
Background: Neural components of the fibrous filum terminale (FT) are well known but are considered as embryonic remnants without functionality. Objective: To investigate the ultrastructure of human FT specimens for...
4.
Klinge P, Srivastava V, McElroy A, Leary O, Ahmed Z, Donahue J, et al.
World Neurosurg
. 2022 Mar;
162:e492-e502.
PMID: 35307588
Background: Patients with hypermobile Ehlers-Danlos syndrome (hEDS), a heritable connective tissue disorder, present frequently with symptoms of tethered cord syndrome (TCS) but without a low-lying conus. Currently, surgical treatment of...
5.
Klinge P, McElroy A, Donahue J, Brinker T, Ziya L Gokaslan , Beland M
J Neurosurg Spine
. 2021 May;
35(1):18-24.
PMID: 34020423
Objective: The craniocervical junction (CCJ) is anatomically complex and comprises multiple joints that allow for wide head and neck movements. The thecal sac must adjust to such movements. Accordingly, the...
6.
Beland M, McElroy A, Brinker T, Ziya L Gokaslan , Klinge P
Ultrasound Q
. 2020 Dec;
38(1):49-52.
PMID: 33298792
Ultrasound (US) imaging of the spinal canal is applied in early infants before formation of posterior spine bony elements. Here, we demonstrate for the first time in adult healthy subjects...
7.
Brinker T, Stopa E, Morrison J, Klinge P
Fluids Barriers CNS
. 2014 May;
11:10.
PMID: 24817998
According to the traditional understanding of cerebrospinal fluid (CSF) physiology, the majority of CSF is produced by the choroid plexus, circulates through the ventricles, the cisterns, and the subarachnoid space...
8.
Brinker T, Spader H
Curr Med Chem
. 2014 Feb;
21(23):2583-90.
PMID: 24533806
Peptides have a great potential for the treatment of neurological disorders, but the clinical translation is still facing significant hurdles. Delivery issues are among them: for example the short systemic...
9.
Wiedmann R, Rosahl S, Brinker T, Samii M, Nakamura M
Exp Brain Res
. 2013 Jul;
229(4):595-607.
PMID: 23831847
In our study we examined acute and chronic changes in c-Fos expression patterns in the visual system of the rat after complete visual deafferentation. In 20 male Lewis rats, the...
10.
Knippenberg S, Thau N, Dengler R, Brinker T, Petri S
PLoS One
. 2012 Jun;
7(6):e36857.
PMID: 22745655
Background: As pharmacological therapies have largely failed so far, stem cell therapy has recently come into the focus of ALS research. Neuroprotective potential was shown for several types of stem...