Thomas A Sasani
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Explore the profile of Thomas A Sasani including associated specialties, affiliations and a list of published articles.
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16
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1117
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Recent Articles
11.
Gao Z, Moorjani P, Sasani T, Pedersen B, Quinlan A, Jorde L, et al.
Proc Natl Acad Sci U S A
. 2019 Apr;
116(19):9491-9500.
PMID: 31019089
The textbook view that most germline mutations in mammals arise from replication errors is indirectly supported by the fact that there are both more mutations and more cell divisions in...
12.
Sasani T, Cone K, Quinlan A, Elde N
Elife
. 2018 Aug;
7.
PMID: 30156554
Poxvirus adaptation can involve combinations of recombination-driven gene copy number variation and beneficial single nucleotide variants (SNVs) at the same loci. How these distinct mechanisms of genetic diversification might simultaneously...
13.
Belyeu J, Nicholas T, Pedersen B, Sasani T, Havrilla J, Kravitz S, et al.
Gigascience
. 2018 Jun;
7(7).
PMID: 29860504
SV-plaudit is a framework for rapidly curating structural variant (SV) predictions. For each SV, we generate an image that visualizes the coverage and alignment signals from a set of samples....
14.
Jain M, Koren S, Miga K, Quick J, Rand A, Sasani T, et al.
Nat Biotechnol
. 2018 Feb;
36(4):338-345.
PMID: 29431738
We report the sequencing and assembly of a reference genome for the human GM12878 Utah/Ceph cell line using the MinION (Oxford Nanopore Technologies) nanopore sequencer. 91.2 Gb of sequence data,...
15.
Feusier J, Witherspoon D, Watkins W, Goubert C, Sasani T, Jorde L
Mob DNA
. 2017 Aug;
8:9.
PMID: 28770012
Background: Polymorphic human elements are excellent tools for assessing population structure, and new retrotransposition events can contribute to disease. Next-generation sequencing has greatly increased the potential to discover elements in...
16.
Piasecki B, Sasani T, Lessenger A, Huth N, Farrell S
Cytoskeleton (Hoboken)
. 2017 Jul;
74(10):390-402.
PMID: 28745435
Cilia are conserved cellular structures that facilitate sensory-based processes, including those required for neuronal and kidney functions. Here, we show that the human mitogen activated kinase-15 (MAPK-15) ortholog in Caenorhabditis...