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Thomas A Ficht

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Articles 61
Citations 1258
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Recent Articles
1.
Cabello A, Wells K, Peng W, Feng H, Wang J, Meyer D, et al.
Cell Host Microbe . 2024 Mar; 32(4):588-605.e9. PMID: 38531364
Many powerful methods have been employed to elucidate the global transcriptomic, proteomic, or metabolic responses to pathogen-infected host cells. However, the host glycome responses to bacterial infection remain largely unexplored,...
2.
Benn J, Nunez C, Blue-McLendon A, Chaki S, Ficht T, Rice-Ficht A, et al.
J Zoo Wildl Med . 2024 Mar; 55(1):212-218. PMID: 38453505
Improved methods are needed to prevent wildlife deaths from anthrax. Caused by , naturally occurring outbreaks of anthrax are frequent but unpredictable. The commercially available veterinary vaccine is labeled for...
3.
Nunez C, Benn J, Blue-McLendon A, Chaki S, Ficht T, Rice-Ficht A, et al.
J Wildl Dis . 2023 Nov; 60(1):179-183. PMID: 37921658
Outbreaks of anthrax, caused by the soilborne bacterium Bacillus anthracis, are a continuous threat to free-ranging livestock and wildlife in enzootic regions of the United States, sometimes causing mass mortalities....
4.
Moreno E, Middlebrook E, Altamirano-Silva P, Al Dahouk S, Araj G, Arce-Gorvel V, et al.
J Clin Microbiol . 2023 Jul; 61(8):e0043823. PMID: 37395662
Bacteria of the genus Brucella are facultative intracellular parasites that cause brucellosis, a severe animal and human disease. Recently, a group of taxonomists merged the brucellae with the primarily free-living,...
5.
Plocica J, Guo F, Das J, Kobayashi K, Ficht T, Alaniz R, et al.
J Transl Autoimmun . 2023 Apr; 6:100198. PMID: 37090898
Autoimmune diseases such as rheumatoid arthritis and type 1 diabetes are increasingly common global problems. Concerns about increases in the prevalence of such diseases and the limited efficacy of conventional...
6.
Das J, Guo F, Hunt C, Steinmeyer S, Plocica J, Kobayashi K, et al.
Gut Microbes . 2022 Nov; 14(1):2143222. PMID: 36404471
Immunotherapy has led to impressive advances in the treatment of autoimmune and pro-inflammatory disorders; yet, its clinical outcomes remain limited by a variety of factors including the pro-inflammatory microenvironment (IME)....
7.
Wells K, He K, Pandey A, Cabello A, Zhang D, Yang J, et al.
Elife . 2022 May; 11. PMID: 35587649
The phagocytosis and destruction of pathogens in lysosomes constitute central elements of innate immune defense. Here, we show that , the causative agent of brucellosis, the most prevalent bacterial zoonosis...
8.
Guo F, Das J, Kobayashi K, Qin Q, Ficht T, Alaniz R, et al.
J Immunother Cancer . 2022 Jan; 10(1). PMID: 34987022
The tumor microenvironment (TME) is characterized by the activation of immune checkpoints, which limit the ability of immune cells to attack the growing cancer. To overcome immune suppression in the...
9.
Benn J, Chaki S, Xu Y, Ficht T, Rice-Ficht A, Cook W
NPJ Vaccines . 2021 Aug; 6(1):109. PMID: 34417464
No abstract available.
10.
Ding S, Yang J, Feng X, Pandey A, Barhoumi R, Zhang D, et al.
iScience . 2021 Mar; 24(3):102192. PMID: 33718841
Phagocytosis and autophagy play critical roles in immune defense. The human fungal pathogen (Cn) subverts host autophagy-initiation complex (AIC)-related proteins, to promote its phagocytosis and intracellular parasitism of host cells....