Thirukumaran Kandasamy
Overview
Explore the profile of Thirukumaran Kandasamy including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
33
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Recent Articles
1.
Kandasamy T, Sarkar S, Ghosh S
Chem Biodivers
. 2025 Mar;
:e202402883.
PMID: 40065747
Zinc (Zn) ions play a crucial role in cancer therapy due to their ability to induce reactive oxygen species (ROS) generation, oxidative stress, and ferroptosis. Combining Zn ions with other...
2.
Sarkar S, Kandasamy T, Ghosh S
Biochem Biophys Res Commun
. 2025 Mar;
755:151559.
PMID: 40043619
Histone methylation is a key epigenetic modulation that regulates gene expression and is often associated with the pathogenesis of various cancers, including triple-negative breast cancer (TNBC). Histone methyltransferase, MLL1-WDR5 complex...
3.
Kandasamy T, Sarkar S, Ghosh S
ACS Pharmacol Transl Sci
. 2024 Dec;
7(12):3780-3794.
PMID: 39698277
Breast cancer remains one of the most prevalent and challenging cancers to treat due to its complexity and heterogenicity. Cellular processes such as metabolic reprogramming and epithelial-to-mesenchymal transition (EMT) contribute...
4.
Venkatesh D, Sarkar S, Kandasamy T, Ghosh S
Comput Biol Chem
. 2024 Dec;
115:108312.
PMID: 39689434
The aberrant metabolic reprogramming endows TNBC cells with sufficient ATP and lactate required for survival and metastasis. Hence, the intervention of the metabolic network represents a promising avenue to alleviate...
5.
Ghosh P, Mukhopadhyay S, Kandasamy T, Mondal S, Ghosh S, Iyer P
J Mater Chem B
. 2024 Dec;
13(4):1412-1423.
PMID: 39679875
Understanding molecular motifs that can interfere with amyloid fibrillation through non-covalent interactions is essential for addressing abnormal protein aggregation and associated human diseases. The pursuit of efficient diagnostic and treatment...
6.
Sarkar S, Kandasamy T, Ghosh S
Mol Carcinog
. 2024 Nov;
64(2):344-356.
PMID: 39560382
Breast cancer remains a leading cause of cancer-related mortality among women, with current therapeutic approaches often limited by resistance and recurrence, especially in aggressive subtypes like triple-negative breast cancer. Drug...
7.
Sarkar S, Venkatesh D, Kandasamy T, Ghosh S
Front Biosci (Landmark Ed)
. 2024 Aug;
29(8):287.
PMID: 39206915
Breast cancer, a heterogeneous and intricate disease, ranks among the leading causes of mortality in women. Restricted therapeutic choices, drug resistance, recurrence, and metastasis are the predominant conditions that lead...
8.
Kandasamy T, Sarkar S, Sen P, Venkatesh D, Ghosh S
J Cell Biochem
. 2024 May;
125(7):e30574.
PMID: 38704688
Altered energy metabolism is an emerging hallmark of cancer and plays a pivotal in cell survival, proliferation, and biosynthesis. In a rapidly proliferating cancer, energy metabolism acts in synergism with...
9.
Ghosh P, Shokeen K, Mondal S, Kandasamy T, Kumar S, Ghosh S, et al.
ACS Chem Neurosci
. 2024 Jan;
15(2):268-277.
PMID: 38170988
The emergence of neurodegenerative diseases is connected to several pathogenic factors, including metal ions, amyloidogenic proteins, and reactive oxygen species. Recent studies suggest that cytotoxicity is caused by the small,...
10.
Dutta P, Sen P, Kandasamy T, Ghosh S
Comput Biol Chem
. 2023 Dec;
108:108007.
PMID: 38157661
Androgen Receptor (AR) is overexpressed in almost all the molecular subtypes of breast cancer. Besides aiding the tumorigenic environment of cancer by abnormal cell proliferation, AR also takes part in...