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Thierry Juhel

Explore the profile of Thierry Juhel including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 151
Followers 0
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Recent Articles
1.
Janho Dit Hreich S, Humbert O, Pace-Loscos T, Schiappa R, Juhel T, Ilie M, et al.
Cancers (Basel) . 2024 Jun; 16(12). PMID: 38927931
Methods: This ancillary study includes 195 patients with metastatic non-small-cell lung cancer (NSCLC) treated with ICI in monotherapy, either pembrolizumab or nivolumab. Plasmatic levels of IL-18-related compounds, comprising the inhibitor...
2.
Janho Dit Hreich S, Juhel T, Leroy S, Ghinet A, Brau F, Hofman V, et al.
Elife . 2024 Feb; 12. PMID: 38300690
Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease associated with progressive and irreversible deterioration of respiratory functions that lacks curative therapies. Despite IPF being associated with a dysregulated...
3.
Janho Dit Hreich S, Juhel T, Hofman P, Vouret-Craviari V
Biol Proced Online . 2023 Jan; 25(1):1. PMID: 36600200
Background: P2RX7 is a purinergic receptor with pleiotropic activities that is activated by high levels of extracellular ATP that are found in inflamed tissues. P2RX7 has immunomodulatory and anti-tumor proprieties...
4.
Douguet L, Janho Dit Hreich S, Benzaquen J, Seguin L, Juhel T, Dezitter X, et al.
Nat Commun . 2021 Jan; 12(1):653. PMID: 33510147
Only a subpopulation of non-small cell lung cancer (NSCLC) patients responds to immunotherapies, highlighting the urgent need to develop therapeutic strategies to improve patient outcome. We develop a chemical positive...
5.
Benzaquen J, Janho Dit Hreich S, Heeke S, Juhel T, Lalvee S, Bauwens S, et al.
Theranostics . 2020 Oct; 10(24):10849-10860. PMID: 33042257
The characterization of new theranostic biomarkers is crucial to improving the clinical outcome of patients with advanced lung cancer. Here, we aimed at characterizing the P2RX7 receptor, a positive modulator...
6.
Hichri M, Vassaux G, Guigonis J, Juhel T, Graslin F, Guglielmi J, et al.
J Clin Med . 2020 Jan; 9(2). PMID: 31979418
(1) Background: We recently showed that iodinated contrast media (ICM) reduced thyroid uptake of iodide independently of free iodide through a mechanism different from that of NaI and involving a...
7.
Vassaux G, Zwarthoed C, Signetti L, Guglielmi J, Compin C, Guigonis J, et al.
J Nucl Med . 2017 Oct; 59(1):121-126. PMID: 29051343
Perturbation of thyroid iodide uptake is a well-documented side effect of the use of iodinated contrast media (ICM) administered intravenously. This side effect is thought to be mediated by free...
8.
Bozec A, Zangari J, Butori-Pepino M, Ilie M, Lalvee S, Juhel T, et al.
Oncotarget . 2017 Sep; 8(34):57174-57186. PMID: 28915663
MicroRNAs (miRs) participate in tumor growth and dissemination by regulating expression of various target genes. MiR-223-3p is suspected of being involved in head and neck squamous cell carcinoma (HNSCC) growth...
9.
Hofman P, Cherfils-Vicini J, Bazin M, Ilie M, Juhel T, Hebuterne X, et al.
Cancer Res . 2015 Jan; 75(5):835-45. PMID: 25564520
Colitis-associated cancer (CAC) is a complication of inflammatory bowel disease (IBD). Binding of extracellular ATP to the purinergic receptor P2RX7 has emerged as a critical event in controlling intestinal inflammation,...