Thierry G Pascal
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Explore the profile of Thierry G Pascal including associated specialties, affiliations and a list of published articles.
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11
Citations
463
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Recent Articles
1.
Malvisi L, Yarraguntla A, Mortier M, Osman K, Cleary D, Sente B, et al.
Infect Dis (Lond)
. 2022 Jul;
54(11):784-793.
PMID: 35794793
Background: Bacterial infections are associated with acute exacerbations of chronic obstructive pulmonary disease (AECOPD), but the mechanism is incompletely understood. Method: In a COPD observational study (NCT01360398), sputum samples were...
2.
Tait D, Hatherill M, Van Der Meeren O, Ginsberg A, van Brakel E, Salaun B, et al.
N Engl J Med
. 2019 Oct;
381(25):2429-2439.
PMID: 31661198
Background: Results of an earlier analysis of a trial of the M72/AS01 candidate vaccine against showed that in infected adults, the vaccine provided 54.0% protection against active pulmonary tuberculosis disease,...
3.
Wilkinson T, Aris E, Bourne S, Clarke S, Peeters M, Pascal T, et al.
ERJ Open Res
. 2019 Mar;
5(1).
PMID: 30815467
The association between exacerbation aetiology and exacerbation frequency is poorly understood. We analysed 2-year follow-up data from a prospective observational study of patients with chronic obstructive pulmonary disease (COPD) (www.clinicaltrials.gov...
4.
Osman K, Jefferies J, Woelk C, Devos N, Pascal T, Mortier M, et al.
Sci Rep
. 2018 Oct;
8(1):14734.
PMID: 30282975
H. haemolyticus is often misidentified as NTHi due to their close phylogenetic relationship. Differentiating between the two is important for correct identification and appropriate treatment of infective organism and to...
5.
Maddi S, Kolsum U, Jackson S, Barraclough R, Maschera B, Simpson K, et al.
Int J Chron Obstruct Pulmon Dis
. 2017 Jun;
12:1507-1518.
PMID: 28579769
Background: is commonly isolated from the airways of COPD patients. Antibiotic treatment may cause the emergence of resistant strains, particularly ampicillin-resistant strains, including β-lactamase-negative ampicillin resistance (BLNAR) strains. Genetic identification...
6.
Staples K, Taylor S, Thomas S, Leung S, Cox K, Pascal T, et al.
PLoS One
. 2017 Apr;
12(4):e0176749.
PMID: 28441440
[This corrects the article DOI: 10.1371/journal.pone.0167250.].
7.
Wilkinson T, Aris E, Bourne S, Clarke S, Peeters M, Pascal T, et al.
Thorax
. 2017 Apr;
72(10):919-927.
PMID: 28432209
Background: The aetiology of acute exacerbations of COPD (AECOPD) is incompletely understood. Understanding the relationship between chronic bacterial airway infection and viral exposure may explain the incidence and seasonality of...
8.
Saez-Llorens X, Rowley S, Wong D, Rodriguez M, Calvo A, Troitino M, et al.
Hum Vaccin Immunother
. 2017 Apr;
13(6):1-16.
PMID: 28368738
We previously reported 10-valent pneumococcal non-typeable Haemophilus influenzae (NTHi) protein D conjugate vaccine (PHiD-CV) efficacy in a double-blind randomized trial (ClinicalTrials.gov: NCT00466947) against various diseases, including acute otitis media (AOM)....
9.
Staples K, Taylor S, Thomas S, Leung S, Cox K, Pascal T, et al.
PLoS One
. 2016 Nov;
11(11):e0167250.
PMID: 27898728
Non-typeable Haemophilus influenzae (NTHi) is a key pathogen in COPD, being associated with airway inflammation and risk of exacerbation. Why some patients are susceptible to colonisation is not understood. We...
10.
Pauksens K, Nilsson A, Caubet M, Pascal T, Van Belle P, Poolman J, et al.
Clin Vaccine Immunol
. 2014 Mar;
21(5):651-60.
PMID: 24599529
Six vaccine formulations containing AS02V or alum (aluminum phosphate [AlPO4]) adjuvant with pneumococcal proteins, pneumococcal histidine triad D (PhtD), and/or detoxified pneumolysin (dPly), either as a polysaccharide carrier in an...