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Thibault Helleputte

Explore the profile of Thibault Helleputte including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bastin M, Carr W, Davis C, Fleischer D, Lieberman J, Mustafa S, et al.
Allergy . 2023 Mar; 78(9):2467-2476. PMID: 36916639
Background: Epicutaneous immunotherapy with investigational Viaskin™ Peanut 250 μg (DBV712) has demonstrated statistically superior desensitization versus placebo in peanut-allergic children in clinical trials. It is unclear whether serologic biomarkers predict...
2.
Henrotin Y, Tits C, Paul J, Gramme P, Helleputte T, Migliore A, et al.
Cartilage . 2021 Oct; 13(1_suppl):1696S-1701S. PMID: 34696623
Objectives: This work studied if and how current clinical practice agrees with European Viscosupplementation Consensus Group (EUROVISCO) recommendations and how this agreement might be different according to physician's specialization. In...
3.
Gruson D, Helleputte T, Rousseau P, Gruson D
Clin Biochem . 2019 Apr; 69:1-7. PMID: 31022391
Artificial intelligence (AI) and data science are rapidly developing in healthcare, as is their translation into laboratory medicine. Our review article presents an overview of the data science domain while...
4.
Bonnet N, Paul J, Helleputte T, Veyckemans F, Pirotte T, Pregardien C, et al.
Pediatr Transplant . 2019 Mar; 23(4):e13390. PMID: 30888111
Objectives: Cirrhotic children wait-listed for liver transplant are prone to bleeding from gastrointestinal varices. Grade 2-3 esophageal varices, red signs, and gastric varices are well-known risk factors. However, the involvement...
5.
Olesen T, Denys M, Goessaert A, Bruneel E, Decalf V, Helleputte T, et al.
Int J Clin Pract . 2018 Dec; 73(8):e13306. PMID: 30556626
Purpose: The main objective of our study was to determine which combination of modifiable and non-modifiable parameters that could discriminate patients with nocturia from those without nocturia. This was a...
6.
Litovkin K, Van Eynde A, Joniau S, Lerut E, Laenen A, Gevaert T, et al.
PLoS One . 2015 Jun; 10(6):e0130651. PMID: 26086362
Background: Prostate cancer (PCa) is a very heterogeneous disease with respect to clinical outcome. This study explored differential DNA methylation in a priori selected genes to diagnose PCa and predict...
7.
Lauwerys B, Hernandez-Lobato D, Gramme P, Ducreux J, Dessy A, Focant I, et al.
PLoS One . 2015 May; 10(4):e0122104. PMID: 25927832
Objectives: Early diagnosis of rheumatoid arthritis (RA) is an unmet medical need in the field of rheumatology. Previously, we performed high-density transcriptomic studies on synovial biopsies from patients with arthritis,...
8.
Boidot R, Branders S, Helleputte T, Rubio L, Dupont P, Feron O
Oncotarget . 2014 Sep; 5(16):6947-63. PMID: 25216520
Background: Temporal and local fluctuations in O2 in tumors require adaptive mechanisms to support cancer cell survival and proliferation. The transcriptome associated with cycling hypoxia (CycHyp) could thus represent a...
9.
Wanty C, Helleputte T, Smets F, Sokal E, Stephenne X
J Pediatr Gastroenterol Nutr . 2012 Dec; 56(5):537-43. PMID: 23263589
Objectives: The management of esophageal varices (EV) in children experiencing biliary atresia (BA) remains controversial. Recent studies in children proposed initiating a prophylactic treatment in patients with severe (grade III)...
10.
Abeel T, Helleputte T, Van de Peer Y, Dupont P, Saeys Y
Bioinformatics . 2009 Nov; 26(3):392-8. PMID: 19942583
Motivation: Biomarker discovery is an important topic in biomedical applications of computational biology, including applications such as gene and SNP selection from high-dimensional data. Surprisingly, the stability with respect to...