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Therese Juntti

Explore the profile of Therese Juntti including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 104
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Recent Articles
1.
Efazat G, Novak M, Kaminskyy V, De Petris L, Kanter L, Juntti T, et al.
Oncotarget . 2016 Aug; 7(37):60332-60347. PMID: 27533087
Ephrin receptors (Ephs) are reported to control metastatic signaling of non-small cell lung cancer (NSCLC) and other tumors. Here we show for the first time that blocking expression of the...
2.
Carlier C, Strese S, Viktorsson K, Velander E, Nygren P, Uustalu M, et al.
Oncotarget . 2016 Aug; 7(37):59322-59335. PMID: 27528037
Ovarian cancer carries a significant mortality. Since symptoms tend to be minimal, the disease is often diagnosed when peritoneal metastases are already present. The standard of care in advanced ovarian...
3.
Viktorsson K, Shah C, Juntti T, Haag P, Zielinska-Chomej K, Sierakowiak A, et al.
Mol Oncol . 2016 Feb; 10(5):719-34. PMID: 26827254
Background: Chemotherapy options in advanced urothelial carcinoma (UC) remain limited. Here we evaluated the peptide-based alkylating agent melphalan-flufenamide (mel-flufen) for UC. Methods: UC cell lines J82, RT4, TCCsup and 5637...
4.
Sarikonda G, Fousteri G, Sachithanantham S, Miller J, Dave A, Juntti T, et al.
PLoS One . 2014 Nov; 9(11):e112242. PMID: 25393309
The infusion of ex vivo-expanded autologous T regulatory (Treg) cells is potentially an effective immunotherapeutic strategy against graft-versus-host disease (GvHD) and several autoimmune diseases, such as type 1 diabetes (T1D)....
5.
Lundholm L, Haag P, Juntti T, Lewensohn R, Viktorsson K
Int J Radiat Biol . 2014 Mar; 90(8):718-26. PMID: 24646078
Purpose: We aimed to analyze the activation status of commonly deregulated receptor tyrosine kinases (RTK) in human non-small cell lung cancer (NSCLC) tumor initiating cells (TIC) previously demonstrated to be...
6.
Fousteri G, Jasinski J, Dave A, Nakayama M, Pagni P, Lambolez F, et al.
Diabetes . 2012 Mar; 61(5):1169-79. PMID: 22403296
In diabetic patients and susceptible mice, insulin is a targeted autoantigen. Insulin B chain 9-23 (B:9-23) autoreactive CD4 T cells are key for initiating autoimmune diabetes in NOD mice; however,...
7.
Van Belle T, Esplugues E, Liao J, Juntti T, Flavell R, von Herrath M
J Immunol . 2011 Aug; 187(6):2915-22. PMID: 21832162
Recent studies have shown that IL-17 can contribute beneficially to pathogen defense but also that excessive IL-17 levels are associated with chronic inflammation and autoimmune disorders. To date, the role...
8.
Fousteri G, Dave A, Juedes A, Juntti T, Morin B, Togher L, et al.
PLoS One . 2011 Jan; 6(1):e14502. PMID: 21253594
Background: Memory CD8 T cells form an essential part of protective immunity against viral infections. Antigenic load, costimulation, CD4-help, cytokines and chemokines fluctuate during the course of an antiviral immune...
9.
Fousteri G, Dave A, Juntti T, Morin B, McClure M, von Herrath M
Viral Immunol . 2010 Jun; 23(3):285-94. PMID: 20565292
Impaired antiviral CD8 and CD4 T-cell responses are often associated with chronic viral infections. Cell-intrinsic as well as cell-extrinsic mechanisms are thought to dampen such responses, for example programmed death...
10.
Van Belle T, Juntti T, Liao J, von Herrath M
J Autoimmun . 2009 Dec; 34(4):445-52. PMID: 20004555
Redirection of immune responses by manipulation of antigen-presenting cells is an emerging strategy for immunosuppressive treatment of autoimmune diseases. In vivo expansion of dendritic cells (DC) by Fms-like tyrosine kinase-3...