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Theresa A Ulrich

Explore the profile of Theresa A Ulrich including associated specialties, affiliations and a list of published articles. Areas
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Citations 722
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Recent Articles
1.
Wong S, Ulrich T, Deleyrolle L, MacKay J, Lin J, Martuscello R, et al.
Cancer Res . 2015 Jan; 75(6):1113-22. PMID: 25634210
Tumor-initiating cells (TIC) perpetuate tumor growth, enable therapeutic resistance, and drive initiation of successive tumors. Virtually nothing is known about the role of mechanotransductive signaling in controlling TIC tumorigenesis, despite...
2.
Umesh V, Rape A, Ulrich T, Kumar S
PLoS One . 2014 Jul; 9(7):e101771. PMID: 25000176
The aggressive and rapidly lethal brain tumor glioblastoma (GBM) is associated with profound tissue stiffening and genomic lesions in key members of the epidermal growth factor receptor (EGFR) pathway. Previous...
3.
Ulrich T, Lee T, Shon H, Moon D, Kumar S
Biomaterials . 2011 May; 32(24):5633-42. PMID: 21575987
Cells are strongly influenced by the local structure and mechanics of the extracellular matrix (ECM). We recently showed that adding agarose to soft collagen ECMs can mechanically stiffen these hydrogels...
4.
Ulrich T, Jain A, Tanner K, MacKay J, Kumar S
Biomaterials . 2009 Nov; 31(7):1875-84. PMID: 19926126
The study of how cell behavior is controlled by the biophysical properties of the extracellular matrix (ECM) is limited in part by the lack of three-dimensional (3D) scaffolds that combine...
5.
Ulrich T, de Juan Pardo E, Kumar S
Cancer Res . 2009 May; 69(10):4167-74. PMID: 19435897
Glioblastoma multiforme (GBM) is a malignant astrocytoma of the central nervous system associated with a median survival time of 15 months, even with aggressive therapy. This rapid progression is due...
6.
Carter A, King G, Ulrich T, Halsey W, Alchenberger D, Perkins T
Appl Opt . 2007 Jan; 46(3):421-7. PMID: 17228390
Mechanical drift is a long-standing problem in optical microscopy that occurs in all three dimensions. This drift increasingly limits the resolution of advanced surface-coupled, single-molecule experiments. We overcame this drift...