Theodore Huang
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Explore the profile of Theodore Huang including associated specialties, affiliations and a list of published articles.
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7
Citations
30
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0
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Recent Articles
1.
Bae E, Dias J, Huang T, Chen J, Parmigiani G, Rebbeck T, et al.
bioRxiv
. 2023 Mar;
PMID: 36945459
Many pathogenic sequence variants (PSVs) have been associated with increased risk of cancers. Mendelian risk prediction models use Mendelian laws of inheritance to predict the probability of having a PSV...
2.
Guan Z, Huang T, McCarthy A, Hughes K, Semine A, Uno H, et al.
Cancers (Basel)
. 2023 Feb;
15(4).
PMID: 36831433
Accurate risk stratification is key to reducing cancer morbidity through targeted screening and preventative interventions. Multiple breast cancer risk prediction models are used in clinical practice, and often provide a...
3.
Shyr C, Blackford A, Huang T, Ke J, Ouardaoui N, Trippa L, et al.
Genet Med
. 2022 Aug;
24(10):2155-2166.
PMID: 35997715
Purpose: Models used to predict the probability of an individual having a pathogenic homozygous or heterozygous variant in a mismatch repair gene, such as MMRpro, are widely used. Recently, MMRpro...
4.
McCarthy A, Liu Y, Ehsan S, Guan Z, Liang J, Huang T, et al.
Cancers (Basel)
. 2022 Jan;
14(1).
PMID: 35008209
(1) Background: The purpose of this study is to compare the performance of four breast cancer risk prediction models by race, molecular subtype, family history of breast cancer, age, and...
5.
Lee G, Liang J, Zhang Q, Huang T, Choirat C, Parmigiani G, et al.
Elife
. 2021 Aug;
10.
PMID: 34406119
Identifying individuals who are at high risk of cancer due to inherited germline mutations is critical for effective implementation of personalized prevention strategies. Most existing models focus on a few...
6.
Huang T, Braun D, Lynch H, Parmigiani G
Genet Epidemiol
. 2020 Oct;
45(2):209-221.
PMID: 33030277
Germline mutations in many genes have been shown to increase the risk of developing cancer. This risk can vary across families who carry mutations in the same gene due to...
7.
Huang T, Gorfine M, Hsu L, Parmigiani G, Braun D
Genet Epidemiol
. 2020 Jun;
44(6):564-578.
PMID: 32506746
There are numerous statistical models used to identify individuals at high risk of cancer due to inherited mutations. Mendelian models predict future risk of cancer by using family history with...