Themis Alissafi
Overview
Explore the profile of Themis Alissafi including associated specialties, affiliations and a list of published articles.
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24
Citations
640
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Recent Articles
1.
Tasis A, Papaioannou N, Grigoriou M, Paschalidis N, Loukogiannaki C, Filia A, et al.
Cancer Res Commun
. 2024 Nov;
4(12):3067-3083.
PMID: 39485042
Immunophenotypic analysis identified a BM CD57+CXCR3+ subset of CD8+ T cells associated with response to AZA in patients with MDS and AML. Single-cell RNA sequencing analysis revealed that IFN signaling...
2.
Vetsika E, Fragoulis G, Kyriakidi M, Verrou K, Tektonidou M, Alissafi T, et al.
Front Immunol
. 2024 Jun;
15:1403680.
PMID: 38911848
Objectives: Programmed cell death protein-1 (PD-1) maintains peripheral immune tolerance by preventing T cell continuous activation. Aiming to understand the extent of PD-1 expression in inflammatory arthritis beyond its involvement...
3.
Varveri A, Papadopoulou M, Papadovasilakis Z, Compeer E, Legaki A, Delis A, et al.
Nat Commun
. 2024 Jun;
15(1):4988.
PMID: 38862534
Cancer-associated fibroblasts (CAFs) have emerged as a dominant non-hematopoietic cell population in the tumour microenvironment, serving diverse functions in tumour progression. However, the mechanisms via which CAFs influence the anti-tumour...
4.
Manolakou T, Nikolopoulos D, Gkikas D, Filia A, Samiotaki M, Stamatakis G, et al.
Sci Adv
. 2022 Oct;
8(43):eabo5840.
PMID: 36306362
B cells orchestrate autoimmune responses in patients with systemic lupus erythematosus (SLE), but broad-based B cell-directed therapies show only modest efficacy while blunting humoral immune responses to vaccines and inducing...
5.
Kerdidani D, Papaioannou N, Nakou E, Alissafi T
Biomedicines
. 2022 Sep;
10(9).
PMID: 36140240
Immune-mediated inflammatory diseases (IMIDs) are a group of autoimmune and chronic inflammatory disorders with constantly increasing prevalence in the modern world. The vast majority of IMIDs develop as a consequence...
6.
Frangou E, Garantziotis P, Grigoriou M, Banos A, Nikolopoulos D, Pieta A, et al.
Ann Rheum Dis
. 2022 Jul;
81(10):1409-1419.
PMID: 35906002
Objectives: Patients with lupus nephritis (LN) are in urgent need for early diagnosis and therapeutic interventions targeting aberrant molecular pathways enriched in affected kidneys. Methods: We used mRNA-sequencing in effector...
7.
Hatzioannou A, Boumpas A, Papadopoulou M, Papafragkos I, Varveri A, Alissafi T, et al.
Front Immunol
. 2021 Sep;
12:731947.
PMID: 34539668
Regulatory T (Treg) cells, possess a strategic role in the maintenance of immune homeostasis, and their function has been closely linked to development of diverse pathologies including autoimmunity and cancer....
8.
Kokkinopoulos I, Banos A, Grigoriou M, Filia A, Manolakou T, Alissafi T, et al.
Sci Rep
. 2021 Aug;
11(1):15759.
PMID: 34344937
Systemic lupus erythematosus (SLE) is an autoimmune disease where bone-marrow-derived haematopoietic cells have a key role in its pathogenesis with accumulating evidence suggesting an aberrant function of haematopoietic stem/progenitor cells...
9.
Grigoriou M, Banos A, Hatzioannou A, Kloetgen A, Kouzis P, Aggouraki D, et al.
Cancer Immunol Res
. 2021 Apr;
9(7):726-734.
PMID: 33820810
Immune checkpoint inhibitors (ICI), which target immune regulatory pathways to unleash antitumor responses, have revolutionized cancer immunotherapy. Despite the remarkable success of ICI immunotherapy, a significant proportion of patients whose...
10.
Papaioannou A, Boumpas A, Papadopoulou M, Hatzioannou A, Alissafi T, Verginis P
Methods Mol Biol
. 2020 Nov;
2236:85-98.
PMID: 33237543
Myeloid-derived suppressor cells (MDSC) are potent suppressor cells that accumulate in tumor microenvironment and inhibit anti-tumor responses. Assessment of cell-autonomous MDSC responses allows the precise characterization of MDSCs in various...