Thayse R Bruggemann
Overview
Explore the profile of Thayse R Bruggemann including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
209
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Recent Articles
1.
Bruggemann T, Krishnamoorthy N, Hagner M, Matschiner G, Jaquin T, Tavares L, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Aug;
327(5):L624-L633.
PMID: 39104317
Severe asthma is a syndromic label assigned to patients based on clinical parameters, yet there are diverse underlying molecular endotypes in severe asthma pathobiology. Immunophenotyping of asthma biospecimens commonly includes...
2.
Peh H, Nshimiyimana R, Bruggemann T, Duvall M, Nijmeh J, Serhan C, et al.
FASEB J
. 2024 Jul;
38(14):e23807.
PMID: 38989570
Specialized proresolving mediators (SPMs) promote local macrophage efferocytosis but excess leukocytes early in inflammation require additional leukocyte clearance mechanism for resolution. Here, neutrophil clearance mechanisms from localized acute inflammation were...
3.
Peh H, Bruggemann T, Duvall M, Nshimiyimana R, Nijmeh J, Cinelli M, et al.
Allergy
. 2023 Oct;
79(3):739-743.
PMID: 37888888
No abstract available.
4.
Bruggemann T, Peh H, Tavares L, Nijmeh J, Shay A, Rezende R, et al.
Am J Respir Cell Mol Biol
. 2023 Aug;
69(6):666-677.
PMID: 37552821
Eosinophils (Eos) reside in multiple organs during homeostasis and respond rapidly to an inflammatory challenge. Although Eos share chemical staining properties, they also demonstrate phenotypic and functional plasticity that is...
5.
Krishnamoorthy N, Walker K, Bruggemann T, Tavares L, Smith E, Nijmeh J, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
120(2):e2206480120.
PMID: 36595677
The resolution of infection is an active process with specific molecular and cellular mechanisms that temper inflammation and enhance pathogen clearance. Here, the specialized pro-resolving mediator (SPM) Maresin 1 (MaR1)...
6.
Bruggemann T, Carlo T, Krishnamoorthy N, Duvall M, Abdulnour R, Nijmeh J, et al.
iScience
. 2022 Oct;
25(10):105185.
PMID: 36238896
Lipid phosphate phosphatases are a family of enzymes with diverse cellular metabolic functions. Phospholipid phosphatase 6 (PLPP6) is a regulator of cellular polyisoprenyl phosphates; however, its functions remain to be...
7.
Tavares L, Bruggemann T, Rezende R, G Machado M, Cagnina R, Shay A, et al.
mBio
. 2022 Aug;
13(4):e0126722.
PMID: 35913160
Influenza A virus (IAV) infections are a leading cause of mortality worldwide. Excess mortality during IAV epidemics and pandemics is attributable to secondary bacterial infections, particularly pneumonia caused by Streptococcus...
8.
Puzzovio P, Bruggemann T, Pahima H, Mankuta D, Levy B, Levi-Schaffer F
Pharmacol Res
. 2022 Mar;
178:106172.
PMID: 35278626
Background: Cromolyn Sodium (CS) has been used in the past as an anti-allergy drug owing to its mast cell (MC) stabilizing properties that impair histamine release. However, additional mechanisms for...
9.
Walker K, Krishnamoorthy N, Bruggemann T, Shay A, Serhan C, Levy B
Front Immunol
. 2021 Sep;
12:704427.
PMID: 34489955
Viral pneumonias are a major cause of morbidity and mortality, owing in part to dysregulated excessive lung inflammation, and therapies to modulate host responses to viral lung injury are urgently...
10.
Levy B, Abdulnour R, Tavares A, Bruggemann T, Norris P, Bai Y, et al.
J Allergy Clin Immunol
. 2019 Oct;
145(1):335-344.
PMID: 31622689
Background: Cysteinyl leukotrienes (CysLTs) are potent prophlogistic mediators in asthmatic patients; however, inhibition of CysLT receptor 1 is not a consistently effective treatment, suggesting additional regulatory mechanisms. Other cysteinyl-containing lipid...