Tessy Thomas Maliekal
Overview
Explore the profile of Tessy Thomas Maliekal including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
149
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Datta N, Vp S, Parvathy K, A S S, Maliekal T
Exp Cell Res
. 2024 Aug;
442(1):114213.
PMID: 39173941
Since metastasis accounts for the majority of cancer morbidity and mortality, attempts are focused to block metastasis and metastasis initiating cellular programs. It is generally believed that hypoxia, reactive oxygen...
2.
Sarkar M, Raj R R, Maliekal T
Exp Cell Res
. 2024 Jul;
441(2):114166.
PMID: 39029572
Given the importance of aberrant protein-protein interactions (PPIs) in disease, the recent drug discovery focuses on targeting the altered PPIs to treat the disease. In this context, identifying the atypical...
3.
Nair M, Mavatkar A, Naidu C, V P S, C E A, Rajarajan S, et al.
Cells
. 2024 May;
13(10.
PMID: 38786043
Epigenetic alterations that lead to differential expression of microRNAs (miRNAs/miR) are known to regulate tumour cell states, epithelial-mesenchymal transition (EMT) and the progression to metastasis in breast cancer. This study...
4.
Riya P, Basu B, Surya S, Parvathy S, Lalitha S, Jyothi N, et al.
J Cell Sci
. 2022 Nov;
135(22).
PMID: 36321463
Notch signaling and its downstream gene target HES1 play a critical role in regulating and maintaining cancer stem cells (CSCs), similar to as they do during embryonic development. Here, we...
5.
Maliekal T, Dharmapal D, Sengupta S
Front Immunol
. 2022 Jun;
13:876278.
PMID: 35693789
Although the role of microtubule dynamics in cancer progression is well-established, the roles of tubulin isotypes, their cargos and their specific function in the induction and sustenance of cancer stem...
6.
Dharmapal D, Jyothy A, Mohan A, Balagopal P, George N, Sebastian P, et al.
Front Oncol
. 2022 Jan;
11:788024.
PMID: 35004310
Recent advancements in cancer research have shown that cancer stem cell (CSC) niche is a crucial factor modulating tumor progression and treatment outcomes. It sustains CSCs by orchestrated regulation of...
7.
Senapati P, Bhattacharya A, Das S, Dey S, Sudarshan D, G S, et al.
Mol Cell Biol
. 2021 Dec;
42(2):e0066920.
PMID: 34898280
Nucleophosmin (NPM1) is a multifunctional histone chaperone that can activate acetylation-dependent transcription from chromatin templates . p300-mediated acetylation of NPM1 has been shown to further enhance its transcription activation potential....
8.
Gopalakrishnan S, Uma S, Mohan G, Mohan A, Shanmugam G, Kumar V, et al.
Front Immunol
. 2021 Dec;
12:740620.
PMID: 34867962
While the immunomodulatory pathways initiated in immune cells contribute to therapeutic response, their activation in cancer cells play a role in cancer progression. Also, many of the aberrantly expressed immunomodulators...
9.
Mohan A, Raj Rajan R, Mohan G, Kollenchery Puthenveettil P, Maliekal T
Front Cell Dev Biol
. 2021 Jun;
9:668851.
PMID: 34150761
A subpopulation within cancer, known as cancer stem cells (CSCs), regulates tumor initiation, chemoresistance, and metastasis. At a closer look, CSCs show functional heterogeneity and hierarchical organization. The present review...
10.
Mohan A, Raj R R, Mohan G, K P P, Maliekal T
Front Oncol
. 2021 May;
11:669250.
PMID: 33968778
In view of the importance of cancer stem cells (CSCs) in chemoresistance, metastasis and recurrence, the biology of CSCs were explored in detail. Based on that, several modalities were proposed...