Terry D Connell
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Explore the profile of Terry D Connell including associated specialties, affiliations and a list of published articles.
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51
Citations
893
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Recent Articles
1.
King-Lyons N, Bhati A, Hu J, Mandell L, Shenoy G, Willison H, et al.
Toxins (Basel)
. 2024 Jul;
16(7).
PMID: 39057951
Triple-negative breast cancer (TNBC), which constitutes 10-20 percent of all breast cancers, is aggressive, has high metastatic potential, and carries a poor prognosis due to limited treatment options. LT-IIc, a...
2.
Zalem D, Juhas M, Terrinoni M, King-Lyons N, Lebens M, Varrot A, et al.
Glycobiology
. 2022 Jan;
32(5):391-403.
PMID: 34972864
The heat-labile enterotoxins of Escherichia coli and cholera toxin of Vibrio cholerae are related in structure and function. Each of these oligomeric toxins is comprised of one A polypeptide and...
3.
Knapp M, Johnson T, Ritter M, Rainer R, Fiester S, Grier J, et al.
Expert Rev Vaccines
. 2021 Jun;
20(8):975-987.
PMID: 34148503
: Heat-labile enterotoxins (HLTs) and their cognate ganglioside receptors have been extensively studied because of their therapeutic potential. Gangliosides play arole in modulating effector cells of the immune system, and...
4.
Masso-Welch P, Girald Berlingeri S, King-Lyons N, Mandell L, Hu J, Greene C, et al.
Int J Mol Sci
. 2018 Dec;
20(1).
PMID: 30587795
Triple negative breast cancer (TNBC) remains a serious health problem with poor prognosis and limited therapeutic options. To discover novel approaches to treat TNBC, we screened cholera toxin (CT) and...
5.
Samuels S, Alwan Z, Egnin M, Jaynes J, Connell T, Bernard G, et al.
J AIDS Clin Res
. 2017 Dec;
8(10).
PMID: 29226013
Despite advancements in our understanding of HIV-1 pathogenesis, critical virus components for immunity, vaccines trials, and drugs development, challenges remain in the fight against HIV-1. Of great importance is the...
6.
El-Kassas S, Odemuyiwa S, Hajishengallis G, Connell T, Nashar T
J Clin Cell Immunol
. 2017 Feb;
7(6).
PMID: 28149670
Cholecystokinin (CCK) is a neuropeptide that affects growth rate in chickens by regulating appetite. CCK peptides exert their function by binding to two identified receptors, CCKAR and CCKBR in the...
7.
Lee C, Hajishengallis G, Connell T
J Microbiol Biotechnol
. 2017 Feb;
27(4):709-717.
PMID: 28144014
Mucosal tissues are the initial site through which most pathogens invade. As such, vaccines and adjuvants that modulate mucosal immune functions have emerged as important agents for disease prevention. Herein,...
8.
Griffiths K, Ahmed M, Das S, Gopal R, Horne W, Connell T, et al.
Nat Commun
. 2016 Dec;
7:13894.
PMID: 28004802
The development of a tuberculosis (TB) vaccine that induces sterilizing immunity to Mycobacterium tuberculosis infection has been elusive. Absence of sterilizing immunity induced by TB vaccines may be due to...
9.
Lenhard J, Bulitta J, Connell T, King-Lyons N, Landersdorfer C, Cheah S, et al.
J Antimicrob Chemother
. 2016 Sep;
72(1):153-165.
PMID: 27634916
Objectives: The pharmacodynamics of polymyxin/carbapenem combinations against carbapenem-resistant Acinetobacter baumannii (CRAB) are largely unknown. Our objective was to determine whether intensified meropenem regimens in combination with polymyxin B enhance killing...
10.
Greene C, Hu J, Vance D, Rong Y, Mandell L, King-Lyons N, et al.
J Leukoc Biol
. 2016 Apr;
100(2):361-9.
PMID: 27059843
LT-IIb, a type II heat-labile enterotoxin produced by Escherichia coli, is a potent intradermal adjuvant that enhances immune responses to coadministered antigens. Although the immune mechanisms that promote this augmented...