Teresa P Silva
Overview
Explore the profile of Teresa P Silva including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
184
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Recent Articles
1.
Boutom S, Silva T, Palecek S, Shusta E, Fernandes T, Ashton R
Cell Rep
. 2024 Dec;
43(12):115068.
PMID: 39693224
In recent years, neural organoids derived from human pluripotent stem cells (hPSCs) have offered a transformative pre-clinical platform for understanding central nervous system (CNS) development, disease, drug effects, and toxicology....
2.
Gaudioso A, Silva T, Ledesma M
Adv Drug Deliv Rev
. 2022 Sep;
190:114532.
PMID: 36122863
The lack of available treatments and fatal outcome in most lysosomal storage disorders (LSDs) have spurred research on pathological mechanisms and novel therapies in recent years. In this effort, experimental...
3.
Esperto L, Figueira I, Mascarenhas J, Silva T, Correia J, Neves F
Materials (Basel)
. 2022 Jun;
15(11).
PMID: 35683139
One of the areas of research on materials for thin-film solar cells focuses on replacing In and Ga with more earth-abundant elements. In that respect, chalcostibite (CuSbS) is being considered...
4.
Lee B, Jung S, Hashimura Y, Lee M, Borys B, Dang T, et al.
Bioengineering (Basel)
. 2022 Mar;
9(3).
PMID: 35324781
Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of diseases and vast numbers of patients globally....
5.
Miranda C, Akenhead M, Silva T, Derr M, Vemuri M, Cabral J, et al.
Front Cell Neurosci
. 2022 Mar;
16:838217.
PMID: 35308123
The demand for large cell numbers for cellular therapies and drug screening applications requires the development of scalable platforms capable of generating high-quality populations of tissue-specific cells derived from human...
6.
Silva T, Pereira C, Raposo A, Oliveira A, Arez M, Cabral J, et al.
Stem Cell Res
. 2021 Jun;
53:102364.
PMID: 34087993
Women who inherit heterozygous mutations in the BRCA2 gene have an increased risk of developing cancer, mainly breast and ovarian tumors. A particular BRCA2 mutation (c.156_157insAlu) is exclusively found in...
7.
Silva T, Sousa-Luis R, Fernandes T, Bekman E, Rodrigues C, Vaz S, et al.
Biotechnol Bioeng
. 2021 Apr;
118(7):2781-2803.
PMID: 33871054
Human-induced pluripotent stem cells (iPSCs) have great potential for disease modeling. However, generating iPSC-derived models to study brain diseases remains a challenge. In particular, the ability to recapitulate cerebellar development...
8.
Silva T, Pereira C, Oliveira A, Raposo A, Arez M, Cabral J, et al.
Stem Cell Res
. 2021 Feb;
52:102242.
PMID: 33631522
How BRCA1 germline mutations predispose to cancer remains poorly understood. Induced pluripotent stem cells (iPSCs) represent an emerging model to investigate the molecular mechanisms underlying malignant transformation in primary cells...
9.
Gomes A, Fernandes T, Vaz S, Silva T, Bekman E, Xapelli S, et al.
Front Cell Dev Biol
. 2020 Dec;
8:610427.
PMID: 33363173
Engineering brain organoids from human induced pluripotent stem cells (hiPSCs) is a powerful tool for modeling brain development and neurological disorders. Rett syndrome (RTT), a rare neurodevelopmental disorder, can greatly...
10.
Barros I, Marcelo A, Silva T, Barata J, Rufino-Ramos D, de Almeida L, et al.
Front Cell Neurosci
. 2020 Nov;
14:584277.
PMID: 33132851
Polyglutamine (polyQ) diseases are a group of inherited neurodegenerative disorders caused by the expansion of the cytosine-adenine-guanine (CAG) repeat. This mutation encodes extended glutamine (Q) tract in the disease protein,...