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Telma Quintela

Explore the profile of Telma Quintela including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 318
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Recent Articles
1.
Mineiro R, Rodrigues Cardoso M, Duarte A, Santos C, Cipolla-Neto J, do Amaral F, et al.
Front Neuroendocrinol . 2024 Oct; 75:101158. PMID: 39395545
The blood-brain barrier and the blood-cerebrospinal fluid barrier separate the blood from brain tissue and cerebrospinal fluid. These brain barriers are important to maintain homeostasis and complex functions by protecting...
2.
Mineiro R, Rodrigues Cardoso M, Pinheiro J, Cipolla-Neto J, do Amaral F, Quintela T
Adv Protein Chem Struct Biol . 2024 Jul; 142:163-190. PMID: 39059985
Melatonin is an indolamine secreted to circulation by the pineal gland according to a circadian rhythm. Melatonin levels are higher during nighttime, and the principal function of this hormone is...
3.
Furtado A, Duarte A, Costa A, Goncalves I, Santos C, Gallardo E, et al.
Int J Mol Sci . 2024 May; 25(9). PMID: 38732233
Donepezil (DNPZ) is a cholinesterase inhibitor used for the management of Alzheimer's disease (AD) and is dependent on membrane transporters such as ABCG2 to actively cross brain barriers and reach...
4.
Furtado A, Costa D, Lemos M, Cavaco J, Santos C, Quintela T
Adv Protein Chem Struct Biol . 2023 Sep; 137:39-81. PMID: 37709381
Molecular clocks are responsible for defining 24-h cycles of behaviour and physiology that are called circadian rhythms. Several structures and tissues are responsible for generating these circadian rhythms and are...
5.
Mineiro R, Albuquerque T, Neves A, Santos C, Costa D, Quintela T
Int J Mol Sci . 2023 Aug; 24(16). PMID: 37628722
For brain protection, the blood-brain barrier and blood-cerebrospinal fluid barrier limit the traffic of molecules between blood and brain tissue and between blood and cerebrospinal fluid, respectively. Besides their protective...
6.
Albuquerque T, Neves A, Paul M, Biswas S, Vuelta E, Garcia-Tunon I, et al.
J Funct Biomater . 2023 Jul; 14(7). PMID: 37504857
The circadian clock controls behavior and physiology. Presently, there is clear evidence of a connection between this timing system and cancer development/progression. Moreover, circadian rhythm consideration in the therapeutic action...
7.
Santos C, Cipolla-Neto J, Krohn M, Goncalves I, Quintela T
Front Neurosci . 2023 Apr; 17:1176084. PMID: 37051143
No abstract available.
8.
Mineiro R, Santos C, Goncalves I, Lemos M, Cavaco J, Quintela T
J Physiol Biochem . 2023 Mar; 79(3):467-487. PMID: 36995571
Drug efficacy is dependent on the pharmacokinetics and pharmacodynamics of therapeutic agents. Tight junctions, detoxification enzymes, and drug transporters, due to their localization on epithelial barriers, modulate the absorption, distribution,...
9.
Furtado A, Esgalhado A, Duarte A, Costa A, Costa-Brito A, Carro E, et al.
J Neurosci Res . 2022 Dec; 101(4):524-540. PMID: 36583371
The choroid plexus (CP) is part of the blood-cerebrospinal fluid barrier (BCSFB) and was recently described as an important component of the circadian clock system. It is the principal source...
10.
Neves A, Albuquerque T, Quintela T, Costa D
J Cell Physiol . 2022 Jun; 237(8):3239-3256. PMID: 35696609
The circadian system is responsible for internal functions and regulation of the organism according to environmental cues (zeitgebers). Circadian rhythm dysregulation or chronodisruption has been associated with several diseases, from...