Tatyana Y Belenkaya
Overview
Explore the profile of Tatyana Y Belenkaya including associated specialties, affiliations and a list of published articles.
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11
Citations
883
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Recent Articles
1.
Li X, Wu Y, Shen C, Belenkaya T, Ray L, Lin X
Biochem Biophys Res Commun
. 2015 May;
463(4):483-9.
PMID: 26002470
The Wnt signaling pathway is crucial for development and disease. The regulation of Wnt protein trafficking is one of the pivotal issues in the Wnt research field. Here we performed...
2.
Tang X, Wu Y, Belenkaya T, Huang Q, Ray L, Qu J, et al.
Dev Biol
. 2012 Jan;
364(1):32-41.
PMID: 22285813
Wnt members act as morphogens essential for embryonic patterning and adult homeostasis. Currently, it is still unclear how Wnt secretion and its gradient formation are regulated. In this study, we...
3.
Zhang P, Wu Y, Belenkaya T, Lin X
Cell Res
. 2011 Nov;
21(12):1677-90.
PMID: 22041890
Drosophila Wingless (Wg) acts as a morphogen during development. Wg secretion is controlled by a seven-pass transmembrane cargo Wntless (Wls). We have recently identified retromer as a key regulator involved...
4.
Wu Y, Belenkaya T, Lin X
Methods Enzymol
. 2010 Sep;
480:33-50.
PMID: 20816203
Heparan sulfate proteoglycans (HSPGs) are cell-surface and extracellular matrix (ECM) macromolecules that comprise a core protein to which heparan sulfate (HS) glycosaminoglycan (GAG) chains are attached. Glypican is a major...
5.
Yan D, Wu Y, Yang Y, Belenkaya T, Tang X, Lin X
Development
. 2010 May;
137(12):2033-44.
PMID: 20501592
Hedgehog (Hh) acts as a morphogen in various developmental contexts to specify distinct cell fates in a concentration-dependent manner. Hh signaling is regulated by two conserved cell-surface proteins: Ig/fibronectin superfamily...
6.
Belenkaya T, Wu Y, Tang X, Zhou B, Cheng L, Sharma Y, et al.
Dev Cell
. 2007 Dec;
14(1):120-31.
PMID: 18160348
Secreted Wnt proteins play essential roles in many biological processes during development and diseases. However, little is known about the mechanism(s) controlling Wnt secretion. Recent studies have identified Wntless (Wls)...
7.
Han C, Yan D, Belenkaya T, Lin X
Development
. 2005 Jan;
132(4):667-79.
PMID: 15647319
Drosophila Wingless (Wg) is the founding member of the Wnt family of secreted proteins. During the wing development, Wg acts as a morphogen whose concentration gradient provides positional cues for...
8.
Belenkaya T, Han C, Yan D, Opoka R, Khodoun M, Liu H, et al.
Cell
. 2004 Oct;
119(2):231-44.
PMID: 15479640
The Drosophila transforming growth factor beta (TGF-beta) homolog Decapentaplegic (Dpp) acts as a morphogen that forms a long-range concentration gradient to direct the anteroposterior patterning of the wing. Both planar...
9.
Han C, Belenkaya T, Khodoun M, Tauchi M, Lin X, Lin X
Development
. 2004 Mar;
131(7):1563-75.
PMID: 14998928
Heparan sulfate proteoglycans (HSPG) have been implicated in regulating the signalling activities of secreted morphogen molecules including Wingless (Wg), Hedgehog (Hh) and Decapentaplegic (Dpp). HSPG consists of a protein core...
10.
Han C, Belenkaya T, Wang B, Lin X
Development
. 2004 Jan;
131(3):601-11.
PMID: 14729575
The signalling molecule Hedgehog (Hh) functions as a morphogen to pattern a field of cells in animal development. Previous studies in Drosophila have demonstrated that Tout-velu (Ttv), a heparan sulphate...