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Tatyana L Azhikina

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Citations 196
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Recent Articles
1.
Grigorov A, Skvortsova Y, Bychenko O, Aseev L, Koledinskaya L, Boni I, et al.
Int J Mol Sci . 2023 Aug; 24(16). PMID: 37628885
Bacterial adaptation to cold stress requires wide transcriptional reprogramming. However, the knowledge of molecular mechanisms underlying the cold stress response of mycobacteria is limited. We conducted comparative transcriptomic analysis of...
2.
Martini B, Grigorov A, Skvortsova Y, Bychenko O, Salina E, Azhikina T
Int J Mol Sci . 2023 May; 24(9). PMID: 37175635
In the course of evolution, (Mtb), the etiological agent of tuberculosis, has developed sophisticated strategies to evade host immune response, including the synthesis of small non-coding RNAs (sRNAs), which regulate...
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Bychenko O, Khrulev A, Svetlova J, Tsvetkov V, Kamzeeva P, Skvortsova Y, et al.
Nucleic Acids Res . 2023 Feb; 51(6):2586-2601. PMID: 36840712
Progress in RNA metabolism and function studies relies largely on molecular imaging systems, including those comprising a fluorogenic dye and an aptamer-based fluorescence-activating tag. G4 aptamers of the Mango family,...
5.
Vavilova J, Boyko A, Troyanova N, Ponomareva N, Fokin V, Fedotova E, et al.
Biomolecules . 2022 Apr; 12(4). PMID: 35454081
Parkinson disease (PD) is attributed to a proteostasis disorder mediated by α-synuclein accumulating in a specific brain region. PD manifestation is often related to extraneuronal alterations, some of which could...
6.
Ostrik A, Azhikina T, Salina E
Biochemistry (Mosc) . 2021 Apr; 86(Suppl 1):S109-S119. PMID: 33827403
Mycobacterium tuberculosis possesses a significant arsenal of strategies to combat immune defense of the host organism. Small noncoding RNAs, which constitute the largest group of regulatory RNAs, play an important...
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Ponomaryova A, Rykova E, Gervas P, Cherdyntseva N, Mamedov I, Azhikina T
Cells . 2020 Sep; 9(9). PMID: 32887319
Cancer remains one of the main causes of human mortality despite significant progress in its diagnostics and therapy achieved in the past decade. Massive hypomethylation of retrotransposons, in particular LINE-1,...
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Ponomaryova A, Rykova E, Azhikina T, Bondar A, Cheremisina O, Rodionov E, et al.
Eur J Cancer Prev . 2020 Jun; 30(2):127-131. PMID: 32516173
Along with other malignant diseases, lung cancer arises from the precancerous lung tissue state. Aberrant DNA methylation (hypermethylation of certain genes and hypomethylation of retrotransposons) is known as one of...
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Skvortsova Y, Salina E, Burakova E, Bychenko O, Stetsenko D, Azhikina T
Front Pharmacol . 2019 Oct; 10:1049. PMID: 31632266
The worldwide spread of multidrug-resistant strains prompted the development of new strategies to combat tuberculosis, one of which is antisense therapy based on targeting bacterial mRNA by oligonucleotide derivatives. However,...
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Salina E, Grigorov A, Bychenko O, Skvortsova Y, Mamedov I, Azhikina T, et al.
Front Cell Infect Microbiol . 2019 Aug; 9:272. PMID: 31428590
Under unfavorable conditions such as host immune responses and environmental stresses, human pathogen may acquire the dormancy phenotype characterized by "non-culturability" and a substantial decrease of metabolic activity and global...