Tatiana Yakovleva
Overview
Explore the profile of Tatiana Yakovleva including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
33
Citations
549
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Sokolov V, Yakovleva T, Penland R, Boulton D, Tang W
Front Pharmacol
. 2023 Nov;
14:1229255.
PMID: 37954838
Dapagliflozin-induced improvement of glycemic control in patients with inadequately controlled type 1 diabetes (T1D) is complicated by the delicate balance between blood glucose and exogenous insulin. In this work, we...
2.
Sokolov V, Yakovleva T, Stolbov L, Penland R, Boulton D, Parkinson J, et al.
CPT Pharmacometrics Syst Pharmacol
. 2023 Mar;
12(6):831-841.
PMID: 36912425
Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by abnormally high blood glucose concentrations due to dysfunction of the insulin-producing beta-cells in the pancreas. Dapagliflozin, an inhibitor of...
3.
Karatza E, Yakovleva T, Adams K, Rao G, Ait-Oudhia S
J Pharmacokinet Pharmacodyn
. 2022 Apr;
49(4):397-400.
PMID: 35474412
Pharmacometrics is a constantly evolving field that plays a major role in decision making in drug development and clinical monitoring. Scientists in Pharmacometrics, especially in their early phases of career,...
4.
Menon M, Yakovleva T, Ronkina N, Suwandi A, Odak I, Dhamija S, et al.
Front Cell Dev Biol
. 2022 Jan;
9:795798.
PMID: 35071236
By crossing -floxed mice with -Cre mice carrying the Cre recombinase inserted in the Lysozyme-M () gene locus we aimed the specific deletion of septin7 in myeloid cells, such as...
5.
Shah M, Stolbov L, Yakovleva T, Tang W, Sokolov V, Penland R, et al.
Diabetes Obes Metab
. 2020 Dec;
23(4):991-1000.
PMID: 33368935
Aims: To develop a quantitative systems pharmacology model to describe the effect of dapagliflozin (a sodium-glucose co-transporter-2 [SGLT2] inhibitor) on glucose-insulin dynamics in type 2 diabetes mellitus (T2DM) patients, and...
6.
Sokolov V, Yakovleva T, Chu L, Tang W, Greasley P, Johansson S, et al.
CPT Pharmacometrics Syst Pharmacol
. 2020 Feb;
9(4):222-229.
PMID: 32064793
The aim of this research was to differentiate dapagliflozin, empagliflozin, and canagliflozin based on their capacity to inhibit sodium-glucose cotransporter (SGLT) 1 and 2 in patients with type 2 diabetes...
7.
Ronkina N, Shushakova N, Tiedje C, Yakovleva T, Tollenaere M, Scott A, et al.
J Immunol
. 2019 Sep;
203(8):2291-2300.
PMID: 31527197
Tristetraprolin (TTP) is an RNA-binding protein and an essential factor of posttranscriptional repression of cytokine biosynthesis in macrophages. Its activity is temporally inhibited by LPS-induced p38/MAPKAPK2/3-mediated phosphorylation, leading to a...
8.
Yakovleva T, Sokolov V, Chu L, Tang W, Greasley P, Peilot Sjogren H, et al.
Diabetes Obes Metab
. 2019 Aug;
21(12):2684-2693.
PMID: 31423699
Aim: To develop a quantitative drug-disease systems model to investigate the paradox that sodium-glucose co-transporter (SGLT)2 is responsible for >80% of proximal tubule glucose reabsorption, yet SGLT2 inhibitor treatment results...
9.
Helmlinger G, Sokolov V, Peskov K, Hallow K, Kosinsky Y, Voronova V, et al.
CPT Pharmacometrics Syst Pharmacol
. 2019 May;
8(6):380-395.
PMID: 31087533
Quantitative systems pharmacology (QSP), a mechanistically oriented form of drug and disease modeling, seeks to address a diverse set of problems in the discovery and development of therapies. These problems...
10.
Kononenko O, Watanabe H, Stalhandske L, Zarelius A, Clausen F, Yakovleva T, et al.
Restor Neurol Neurosci
. 2019 Mar;
37(2):87-96.
PMID: 30856132
Background/objectives: Motor impairment induced by traumatic brain injury (TBI) may be mediated through changes in spinal molecular systems regulating neuronal plasticity. We assessed whether a focal controlled cortical impact (CCI)...