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Tatiana Luna-Gomes

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Articles 13
Citations 235
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Recent Articles
1.
Pezzella-Ferreira G, Pao C, Bellas I, Luna-Gomes T, Muniz V, Paiva L, et al.
PLoS Pathog . 2024 Aug; 20(8):e1011812. PMID: 39173086
Identifying new molecular therapies targeted at the severe hepatic fibrosis associated with the granulomatous immune response to Schistosoma mansoni infection is essential to reduce fibrosis-related morbidity/mortality in schistosomiasis. In vitro...
2.
Amorim N, Souza-Almeida G, Luna-Gomes T, Bozza P, Canetti C, Diaz B, et al.
Front Endocrinol (Lausanne) . 2020 Oct; 11:572113. PMID: 33117286
Eosinophils are key regulators of adipose tissue homeostasis, thus characterization of adipose tissue-related molecular factors capable of regulating eosinophil activity is of great interest. Leptin is known to directly activate...
3.
Barletta A, Alves E Silva T, Talyuli O, Luna-Gomes T, Sim S, Anglero-Rodriguez Y, et al.
PLoS Negl Trop Dis . 2020 Oct; 14(10):e0008706. PMID: 33095767
Prostaglandins (PGs) are immuno-active lipids that mediate the immune response in invertebrates and vertebrates. In insects, PGs play a role on different physiological processes such as reproduction, ion transport and...
4.
Santana P, Luna-Gomes T, Rangel-Ferreira M, Tamura A, Da Graca C, Machado M, et al.
Front Pharmacol . 2020 Apr; 11:301. PMID: 32256366
Silicosis is an occupational lung disease caused by inhalation of silica particles. It is characterized by intense lung inflammation, with progressive and irreversible fibrosis, leading to impaired lung function. Purinergic...
5.
Magalhaes K, Luna-Gomes T, Mesquita-Santos F, Correa R, Assuncao L, Atella G, et al.
Front Immunol . 2019 Feb; 9:3161. PMID: 30740113
Parasite-derived lipids may play important roles in host-pathogen interactions and immune evasion mechanisms. Remarkable accumulation of eosinophils is a characteristic feature of inflammation associated with parasitic disease, especially caused by...
6.
Amorim N, Luna-Gomes T, Gama-Almeida M, Souza-Almeida G, Canetti C, Diaz B, et al.
Front Immunol . 2018 Oct; 9:2139. PMID: 30298073
Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy expenditure. Leptin also regulates the immune response by...
7.
Souza-Almeida G, DAvila H, Almeida P, Luna-Gomes T, Liechocki S, Walzog B, et al.
Front Immunol . 2018 Feb; 9:111. PMID: 29467755
Leptin directly activates macrophages and lymphocytes, but the role of leptin in neutrophil activation and migration is still controversial. Here, we investigate the mechanisms of neutrophil migration induced by leptin....
8.
Luna-Gomes T, Santana P, Coutinho-Silva R
Immunobiology . 2015 May; 220(9):1101-6. PMID: 26024943
Silicosis is a fibrotic lung disease caused by the inhalation of silica particles, and is considered an occupational disease, given that these particles are present in the working environment of...
9.
Paiva L, Coelho K, Luna-Gomes T, El-Cheikh M, Borojevic R, Perez S, et al.
Prostaglandins Leukot Essent Fatty Acids . 2015 Feb; 95:57-62. PMID: 25687497
Hepatic Stellate Cells (HSCs) play a crucial role in pathogenesis of liver inflammation and fibrosis. During chronic liver injury, HSCs lose vitamin A and transform into myofibroblastic cells. In schistosomal...
10.
Luna-Gomes T, Filardy A, Rocha J, Decote-Ricardo D, LaRocque-de-Freitas I, Morrot A, et al.
PLoS One . 2014 Mar; 9(3):e90582. PMID: 24599360
Neutrophils are involved in the initial steps of most responses to pathogens and are essential components of the innate immune response. Due to the ability to produce and release various...