Tatiana A Filippova
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Explore the profile of Tatiana A Filippova including associated specialties, affiliations and a list of published articles.
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6
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Recent Articles
1.
Filippova T, Masamrekh R, Farafonova T, Khudoklinova Y, Shumyantseva V, Moshkovskii S, et al.
Biochemistry (Mosc)
. 2025 Mar;
90(1):120-131.
PMID: 40058978
The proposed approach for determining catalytic activity of the SARS-CoV-2 main protease (M) is based on registration of the peak area of electrochemical oxidation of tyrosine residue in the model...
2.
Filippova T, Masamrekh R, Khudoklinova Y, Shumyantseva V, Kuzikov A
Biochimie
. 2024 Mar;
222:169-194.
PMID: 38494106
We discuss the diverse functions of proteases in the context of their biotechnological and medical significance, as well as analytical approaches used to determine the functional activity of these enzymes....
3.
Kuzikov A, Masamrekh R, Filippova T, Tumilovich A, Strushkevich N, Gilep A, et al.
Biomedicines
. 2024 Jan;
12(1).
PMID: 38255257
We describe a bielectrode system for evaluation of the electrocatalytic activity of cytochrome P450 2E1 (CYP2E1) towards chlorzoxazone. One electrode of the system was employed to immobilize Bactosomes with human...
4.
Filippova T, Masamrekh R, Shumyantseva V, Latsis I, Farafonova T, Ilina I, et al.
Talanta
. 2023 Feb;
257:124341.
PMID: 36821964
In this work, we proposed a biosensor for trypsin proteolytic activity assay using immobilization of model peptides on screen-printed electrodes (SPE) modified with gold nanoparticles (AuNPs) prepared by electrosynthetic method....
5.
Kuzikov A, Filippova T, Masamrekh R, Shumyantseva V
Biophys Chem
. 2022 Sep;
291:106894.
PMID: 36174335
The possibility of the detection of atypical kinetic profiles of drug biotransformation using electrochemical systems based on immobilized cytochromes P450 with phenytoin hydroxylation by cytochrome P450 2C19 (CYP2C19) as an...
6.
Masamrekh R, Filippova T, Sherbakov K, Veselovsky A, Shumyantseva V, Kuzikov A
Fundam Clin Pharmacol
. 2020 Oct;
35(2):423-431.
PMID: 33012006
We have investigated interactions of galeterone and its pharmacologically active metabolite - 3-keto-Δ4-galeterone (D4G) - with one of the key enzymes of corticosteroid biosynthesis - steroid 21-monooxygenase (CYP21A2). It was...
7.
Masamrekh R, Filippova T, Haurychenka Y, Sherbakov K, Veselovsky A, Shumyantseva V, et al.
Steroids
. 2020 Jul;
162:108693.
PMID: 32645328
The interactions of pharmacologically active 3-keto-Δ4-metabolite of anticancer drug abiraterone (D4A) with steroid-metabolizing cytochromes P450 (CYP51A1, CYP11A1, CYP19A1) was studied by absorption spectroscopy and molecular docking. Both abiraterone and D4A...