Tareq B Malas
Overview
Explore the profile of Tareq B Malas including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
390
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0
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Recent Articles
1.
Malas T, Leonhard W, Bange H, Granchi Z, Hettne K, van Westen G, et al.
EBioMedicine
. 2019 Dec;
51:102585.
PMID: 31879244
Background: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is one of the most common causes of end-stage renal failure, caused by mutations in PKD1 or PKD2 genes. Tolvaptan, the only drug...
2.
Malas T, Vlietstra W, Kudrin R, Starikov S, Charrout M, Roos M, et al.
Sci Rep
. 2019 Apr;
9(1):6281.
PMID: 31000794
Compounds that are candidates for drug repurposing can be ranked by leveraging knowledge available in the biomedical literature and databases. This knowledge, spread across a variety of sources, can be...
3.
Abdallah A, Weerdenburg E, Guan Q, Ummels R, Borggreve S, Adroub S, et al.
PLoS One
. 2019 Jan;
14(1):e0211003.
PMID: 30673778
The mycobacterial type VII secretion system ESX-1 is responsible for the secretion of a number of proteins that play important roles during host infection. The regulation of the expression of...
4.
Kunnen S, Malas T, Formica C, Leonhard W, t Hoen P, Peters D
Biomed Pharmacother
. 2018 Oct;
108:1123-1134.
PMID: 30372813
Mutations in the PKD1 or PKD2 genes are the cause of autosomal dominant polycystic kidney disease (ADPKD). The encoded proteins localize within the cell membrane and primary cilia and are...
5.
Kunnen S, Malas T, Semeins C, Bakker A, Peters D
J Cell Physiol
. 2017 Oct;
233(4):3615-3628.
PMID: 29044509
Renal epithelial cells are exposed to mechanical forces due to flow-induced shear stress within the nephrons. Shear stress is altered in renal diseases caused by tubular dilation, obstruction, and hyperfiltration,...
6.
Malas T, Formica C, Leonhard W, Rao P, Granchi Z, Roos M, et al.
Am J Physiol Renal Physiol
. 2017 Feb;
312(4):F806-F817.
PMID: 28148532
Polycystic kidney disease (PKD) is a major cause of end-stage renal disease. The disease mechanisms are not well understood and the pathogenesis toward renal failure remains elusive. In this study,...
7.
Abdallah A, Hill-Cawthorne G, Otto T, Coll F, Guerra-Assuncao J, Gao G, et al.
Sci Rep
. 2015 Oct;
5:15443.
PMID: 26487098
Although Bacillus Calmette-Guérin (BCG) vaccines against tuberculosis have been available for more than 90 years, their effectiveness has been hindered by variable protective efficacy and a lack of lasting memory...
8.
Alzubaidy H, Essack M, Malas T, Bokhari A, Motwalli O, Kamanu F, et al.
Gene
. 2015 Oct;
576(2 Pt 1):626-36.
PMID: 26475934
Mangroves are unique, and endangered, coastal ecosystems that play a vital role in the tropical and subtropical environments. A comprehensive description of the microbial communities in these ecosystems is currently...
9.
Ramaprasad A, Mourier T, Naeem R, Malas T, Moussa E, Panigrahi A, et al.
PLoS One
. 2015 Apr;
10(4):e0124473.
PMID: 25875305
Toxoplasma gondii is an important protozoan parasite that infects all warm-blooded animals and causes opportunistic infections in immuno-compromised humans. Its closest relative, Neospora caninum, is an important veterinary pathogen that...
10.
Reid A, Blake D, Ansari H, Billington K, Browne H, Bryant J, et al.
Genome Res
. 2014 Jul;
24(10):1676-85.
PMID: 25015382
Global production of chickens has trebled in the past two decades and they are now the most important source of dietary animal protein worldwide. Chickens are subject to many infectious...