Tara Spence
Overview
Explore the profile of Tara Spence including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
479
Followers
0
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Related Specialties
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Recent Articles
1.
Spence T, Dubuc A
Clin Lab Med
. 2022 Sep;
42(3):451-468.
PMID: 36150823
Accurate detection of copy number alterations (CNAs) has become increasingly important in clinical oncology for the purpose of diagnosis, prognostication, and disease management. Cytogenetic approaches for the detection of CNAs,...
2.
Selvarajah S, Plante S, Speevak M, Vaags A, Hamelinck D, Butcher M, et al.
JTO Clin Res Rep
. 2021 Sep;
2(8):100212.
PMID: 34590051
Introduction: Genotyping circulating tumor DNA (ctDNA) is a promising noninvasive clinical tool to identify the T790M resistance mutation in patients with advanced NSCLC with resistance to EGFR inhibitors. To facilitate...
3.
Banerjee R, Spence T, Frank S, Pandian R, Hoofnagle A, Argiropoulos B, et al.
J Endocr Soc
. 2021 Sep;
5(9):bvab104.
PMID: 34589658
Circulating plasma vitamin D metabolites are highly bound to vitamin D-binding protein (DBP), also known as roup-specific omponent or Gc-globulin. DBP, encoded by the gene, is a member of the...
4.
Spence T, Perera S, Weiss J, Grenier S, Ranich L, Shepherd F, et al.
J Clin Pathol
. 2020 May;
74(2):91-97.
PMID: 32471890
Aims: Epidermal growth factor receptor () T790M mutations can be detected in the circulating tumour DNA from plasma of patients with non-small cell lung cancer (NSCLC) to triage patients for...
5.
McCarthy A, Capo-Chichi J, Spence T, Grenier S, Stockley T, Kamel-Reid S, et al.
J Pathol Clin Res
. 2018 Nov;
5(2):115-129.
PMID: 30387329
Immunohistochemistry (IHC) for mismatch repair (MMR) proteins is used to identify MMR status: being diffusely positive (intact/retained nuclear staining) or showing loss of nuclear tumour staining (MMR protein deficient). Four...
6.
Dunne M, Dou Y, Drake D, Spence T, Gontijo S, Wells P, et al.
J Control Release
. 2018 Apr;
282:35-45.
PMID: 29673642
Triple negative breast cancer is an aggressive disease that accounts for at least 15% of breast cancer diagnoses, and a disproportionately high percentage of breast cancer related morbidity. Intensive research...
7.
Roussos J, Zahedi P, Spence T, Swanson L, Li-Cheung F, Cops F, et al.
Pract Radiat Oncol
. 2016 Aug;
7(1):e77-e83.
PMID: 27552810
Purpose: An audit was conducted of patient schedules for computed tomography simulation (CT-Sim) scans within the Radiation Medicine Program at the Princess Margaret Cancer Centre to investigate opportunities for improved...
8.
Spence T, Bruce J, Yip K, Liu F
Cancers (Basel)
. 2016 Aug;
8(8).
PMID: 27527216
Head and neck cancers (HNCs) are a highly heterogeneous group of tumours that are associated with diverse clinical outcomes. Recent evidence has demonstrated that human papillomavirus (HPV) is involved in...
9.
Kinoshita T, Yip K, Spence T, Liu F
J Hum Genet
. 2016 Jul;
62(1):67-74.
PMID: 27383658
Extracellular vesicles (EV) are small membrane-bound structures that are secreted by various cell types, including tumor cells. Recent studies have shown that EVs are important for cell-to-cell communication, locally and...
10.
Spence T, Bruce J, Yip K, Liu F
Chin Clin Oncol
. 2016 Apr;
5(2):17.
PMID: 27121877
It is becoming increasingly evident that aberrantly expressed microRNAs (miRNAs) are responsible for a number of disease processes, including cancer initiation and progression. miRNAs have been implicated as key players...