Taniya Bhardwaj
Overview
Explore the profile of Taniya Bhardwaj including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
163
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Recent Articles
1.
Kumar P, Saumya K, Bhardwaj T, Giri R
Biophys Chem
. 2024 Dec;
318:107384.
PMID: 39724814
Despite being mostly neglected in structural biology, the C-terminal Regions (CTRs) are studied to be multifunctional in humans as well as in viruses. Previously, SARS-CoV-2 Spike and NSP1 proteins' CTRs...
2.
Giri R, Bhardwaj T, Kapuganti S, Saumya K, Sharma N, Bhardwaj A, et al.
Protein Sci
. 2023 Nov;
32(12):e4833.
PMID: 37937856
Viral pathogenesis typically involves numerous molecular mechanisms. Protein aggregation is a relatively unknown characteristic of viruses, despite the fact that viral proteins have been shown to form terminally misfolded forms....
3.
Bhardwaj T, Giri R
ACS Chem Neurosci
. 2023 Oct;
14(20):3818-3825.
PMID: 37802503
ADAM 17, a disintegrin and metalloproteinase 17 belonging to the adamalysin protein family, is a Zn-dependent type-I transmembrane α-secretase protein. As a major sheddase, ADAM 17 acts as an indispensable...
4.
Bhardwaj T, Gadhave K, Kapuganti S, Kumar P, Faidon Brotzakis Z, Saumya K, et al.
Nat Commun
. 2023 Feb;
14(1):945.
PMID: 36806058
The phenomenon of protein aggregation is associated with a wide range of human diseases. Our knowledge of the aggregation behaviour of viral proteins, however, is still rather limited. Here, we...
5.
Yadav P, Beura S, Panigrahi A, Bhardwaj T, Giri R, Singh S
Blood Cells Mol Dis
. 2022 Sep;
98:102701.
PMID: 36057195
Platelet-derived microvesicles (PMVs) are the most abundant microvesicles in circulation, originating from blood platelets via membrane blebbing. PMVs act as biological cargo carrying key molecules from platelets, including immunomodulatory molecules,...
6.
Bhardwaj T, Kumar P, Giri R
Virology
. 2022 Aug;
575:20-35.
PMID: 36037701
Zika virus (ZIKV) NS4B protein is a membranotropic multifunctional protein. Despite its versatile functioning, its topology and dynamics are not entirely understood. There is no X-ray or cryo-EM structure available...
7.
Kapuganti S, Bhardwaj A, Kumar P, Bhardwaj T, Nayak N, Uversky V, et al.
Expert Rev Proteomics
. 2022 Jun;
19(3):183-196.
PMID: 35655146
Introduction: The life cycle of a virus involves interacting with the host cell, entry, hijacking host machinery for viral replication, evading the host's immune system, and releasing mature virions. However,...
8.
Kumar P, Bhardwaj T, Giri R
RSC Adv
. 2022 Apr;
12(9):5648-5655.
PMID: 35425590
One of the major virulence factors of SARS-CoV-2, NSP1, is a vital drug target due to its role in host immune evasion through multiple pathways. NSP1 protein is associated with...
9.
Kumar P, Bhardwaj T, Garg N, Giri R
Virology
. 2021 Dec;
566:42-55.
PMID: 34864296
All available SARS-CoV-2 spike protein crystal and cryo-EM structures have shown missing electron densities for cytosolic C-terminal regions (CTR). Generally, the missing electron densities point towards the intrinsically disordered nature...
10.
Kumar P, Bhardwaj T, Kumar A, Garg N, Giri R
J Biomol Struct Dyn
. 2021 Jul;
40(21):10763-10770.
PMID: 34320905
Currently, several vaccines and antivirals across the globe are in clinical trials. Hydroxychloroquine (HCQ) was reported to inhibit the SARS-CoV-2 virus in antiviral assays. Here, it raises the curiosity about...