Tania R Mutchie
Overview
Explore the profile of Tania R Mutchie including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
10
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Recent Articles
1.
Yu O, Webb D, Di Milo E, Mutchie T, Teske K, Chen T, et al.
Bioorg Chem
. 2021 Sep;
116:105310.
PMID: 34482171
We describe the synthesis and broad profiling of calcitroic acid (CTA) as vitamin D receptor (VDR) ligand. The x-ray co-crystal structure of the Danio Rerio VDR ligand binding domain in...
2.
Yu O, Mutchie T, Di Milo E, Arnold L
Steroids
. 2019 Nov;
154:108536.
PMID: 31704333
Herein, we describe the synthesis of calcioic acid following a recently developed synthetic strategy for calcitroic acid. Several improvements to reaction conditions were made, which resulted in higher yields. The...
3.
Mutchie T, Yu O, Di Milo E, Arnold L
Mol Cell Endocrinol
. 2019 Jan;
485:1-8.
PMID: 30654005
In recent decades, the majority of ligands developed for the vitamin D receptor (VDR) bind at its deeply buried genomic ligand binding pocket. Theses ligands can be categorized into agonists...