Tania Nolan
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Explore the profile of Tania Nolan including associated specialties, affiliations and a list of published articles.
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28
Citations
8414
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Recent Articles
1.
Bustin S, Kirvell S, Nolan T, Shipley G
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474020
Versatility, sensitivity, and accuracy have made the real-time polymerase chain reaction (qPCR) a crucial tool for research, as well as diagnostic applications. However, for point-of-care (PoC) use, traditional qPCR faces...
2.
Bustin S, Bustin C, Kirvell S, Nolan T, Mueller R, Shipley G
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955620
The COVID-19 pandemic resulted in a universal, immediate, and vast demand for comprehensive molecular diagnostic testing, especially real-time quantitative (qPCR)-based methods. This rapidly triggered a global shortage of testing capacity,...
3.
Bustin S, Shipley G, Kirvell S, Mueller R, Nolan T
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163227
Reverse transcription of RNA coupled to amplification of the resulting cDNA by the polymerase chain reaction (RT-PCR) is one of the principal molecular technologies in use today, with applications across...
4.
Whale A, von der Heide E, Kohlenberg M, Brinckmann A, Baedker S, Karalay O, et al.
Methods
. 2021 Aug;
201:5-14.
PMID: 34454016
Coronavirus disease 2019 (COVID-19) is an infectious, acute respiratory disease caused mainly by person-to-person transmission of the coronavirus SARS-CoV-2. Its emergence has caused a world-wide acute health crisis, intensified by...
5.
Bustin S, Kirvell S, Huggett J, Nolan T
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445406
The reverse transcription quantitative polymerase chain reaction (RT-qPCR) is an established tool for the diagnosis of RNA pathogens. Its potential for automation has caused it to be used as a...
6.
Bustin S, Mueller R, Shipley G, Nolan T
Int J Mol Sci
. 2021 Mar;
22(5).
PMID: 33671091
Although molecular testing, and RT-qPCR in particular, has been an indispensable component in the scientific armoury targeting SARS-CoV-2, there are numerous falsehoods, misconceptions, assumptions and exaggerated expectations with regards to...
7.
Bustin S, Coward A, Sadler G, Teare L, Nolan T
Sci Rep
. 2020 Dec;
10(1):22214.
PMID: 33335187
Accurate, reliable and rapid detection of SARS-CoV-2 is essential not only for correct diagnosis of individual COVID-19 disease but also for the development of a rational strategy aimed at lifting...
8.
Huggett J, Benes V, Bustin S, Garson J, Harris K, Kammel M, et al.
Clin Chem
. 2020 Sep;
66(11):1369-1372.
PMID: 32894756
No abstract available.
9.
Bustin S, Nolan T
Int J Mol Sci
. 2020 Apr;
21(8).
PMID: 32344568
Testing for the presence of coronavirus is an essential diagnostic tool for monitoring and managing the current COVID-19 pandemic. The only reliable test in current use for testing acute infection...
10.
Bustin S, Mueller R, Nolan T
Methods Mol Biol
. 2019 Oct;
2065:5-22.
PMID: 31578684
Primers are critical components of any PCR assay, as they are the main determinants of its specificity, sensitivity, and robustness. Despite the publication of numerous guidelines, the actual design of...