Tanatorn Khotavivattana
Overview
Explore the profile of Tanatorn Khotavivattana including associated specialties, affiliations and a list of published articles.
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22
Citations
133
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Recent Articles
1.
Adediji A, Sroithongmoon A, Suroengrit A, Wilasluck P, Deetanya P, Sanachai K, et al.
Eur J Med Chem
. 2025 Jan;
286:117303.
PMID: 39879938
The severe impact of COVID-19 on global health and economies highlights the critical need for innovative treatments. Recently, lapatinib, a drug initially used for breast cancer, has been identified as...
2.
Ur Rehman M, Chuntakaruk H, Amphan S, Suroengrit A, Hengphasatporn K, Shigeta Y, et al.
ACS Bio Med Chem Au
. 2024 Oct;
4(5):242-256.
PMID: 39431267
Darunavir, a frontline treatment for HIV infection, faces limitations due to emerging multidrug resistant (MDR) HIV strains, necessitating the development of analogs with improved activity. In this study, a combinatorial...
3.
Ereje R, Yahuafai J, Jaroenchuensiri T, Supakijjanusorn P, Unson S, Toopradab B, et al.
ChemMedChem
. 2024 Oct;
20(3):e202400514.
PMID: 39422673
Benzofuropyridines (BFP) are polycyclic compounds with known applications in neuronal diseases. However, its derivatization patterns and anticancer potential remains unexplored. Leveraging the idea of diversity-oriented synthesis (DOS), we developed a...
4.
Chuntakaruk H, Hengphasatporn K, Shigeta Y, Aonbangkhen C, Lee V, Khotavivattana T, et al.
Sci Rep
. 2024 Feb;
14(1):3639.
PMID: 38351065
The prevalence of HIV-1 infection continues to pose a significant global public health issue, highlighting the need for antiretroviral drugs that target viral proteins to reduce viral replication. One such...
5.
Chuntakaruk H, Boonpalit K, Kinchagawat J, Nakarin F, Khotavivattana T, Aonbangkhen C, et al.
J Comput Chem
. 2024 Jan;
45(13):953-968.
PMID: 38174739
In the pursuit of novel antiretroviral therapies for human immunodeficiency virus type-1 (HIV-1) proteases (PRs), recent improvements in drug discovery have embraced machine learning (ML) techniques to guide the design...
6.
Cao V, Loeanurit N, Hengphasatporn K, Hairani R, Wacharachaisurapol N, Prompila N, et al.
Emerg Microbes Infect
. 2023 Oct;
12(2):2270074.
PMID: 37842770
Chikungunya virus is a re-emerging arbovirus that has caused epidemic outbreaks in recent decades. Patients in older age groups with high viral load and severe immunologic response during acute infection...
7.
Patigo A, Hengphasatporn K, Cao V, Paunrat W, Vijara N, Chokmahasarn T, et al.
Sci Rep
. 2022 Dec;
12(1):21646.
PMID: 36517573
Flavone has recently been proved as a promising scaffold for the development of a novel drug against dengue fever, one of the major health threats globally. However, the structure-activity relationship...
8.
Aekrungrueangkit C, Wangngae S, Kamkaew A, Ardkhean R, Thongnest S, Boonsombat J, et al.
Sci Rep
. 2022 Aug;
12(1):13487.
PMID: 35931753
Psoralen derivatives are well known for their unique phototoxicity and also exhibits promising anti-breast cancer activity both in the presence and the absence of UVA irradiation. However, the structure-activity relationship...
9.
Hoarau M, Suwanakitti N, Varatthan T, Thiabma R, Rattanajak R, Charoensetakul N, et al.
Molecules
. 2022 Jun;
27(11).
PMID: 35684452
In the fight towards eradication of malaria, identifying compounds active against new drug targets constitutes a key approach. 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) has been advanced as a promising target, as being part...
10.
Alkyne-Tagged Apigenin, a Chemical Tool to Navigate Potential Targets of Flavonoid Anti-Dengue Leads
Hengphasatporn K, Kaewmalai B, Jansongsaeng S, Badavath V, Saelee T, Chokmahasarn T, et al.
Molecules
. 2021 Nov;
26(22).
PMID: 34834059
A flavonoid is a versatile core structure with various cellular, immunological, and pharmacological effects. Recently, flavones have shown anti-dengue activities by interfering with viral translation and replication. However, the molecular...