Tamsyn Derrick
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Explore the profile of Tamsyn Derrick including associated specialties, affiliations and a list of published articles.
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23
Citations
286
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Recent Articles
11.
Butcher R, Houghton J, Derrick T, Ramadhani A, Herrera B, Last A, et al.
J Microbiol Methods
. 2017 May;
139:95-102.
PMID: 28487054
Introduction: Trachoma, caused by the intracellular bacterium Chlamydia trachomatis (Ct), is the leading infectious cause of preventable blindness. Many commercial platforms are available that provide highly sensitive and specific detection...
12.
Pickering H, Burr S, Derrick T, Makalo P, Joof H, Hayward R, et al.
Parasit Vectors
. 2017 Mar;
10(1):143.
PMID: 28288672
Background: Ocular Chlamydia trachomatis (Ct) infection causes trachoma, the leading infectious cause of blindness. A Ct D/UW3 proteome microarray and sera from Gambian adults with trachomatous trichiasis (TT) or healthy...
13.
Derrick T, Ramadhani A, Mtengai K, Massae P, Burton M, Holland M
Pathog Dis
. 2017 Feb;
75(2).
PMID: 28175294
We previously showed that conjunctival miR-147b and miR-1285 were upregulated in Gambian adults with inflammatory scarring trachoma, and miR-155 and miR-184 expression was strongly associated with conjunctival inflammation and ocular...
14.
Ramadhani A, Derrick T, Macleod D, Holland M, Burton M
PLoS Negl Trop Dis
. 2016 Oct;
10(10):e0005080.
PMID: 27783678
Background: Trachoma is a blinding disease, initiated in early childhood by repeated conjunctival infection with the obligate intracellular bacterium Chlamydia trachomatis. The population prevalence of the clinical signs of active...
15.
Ramadhani A, Derrick T, Holland M, Burton M
PLoS Negl Trop Dis
. 2016 Aug;
10(8):e0004859.
PMID: 27483002
Background: Sight loss from trachoma is the end result of a scarring disease process starting in early childhood and characterised by repeated episodes of conjunctival inflammation (active trachoma). Subsequently, the...
16.
Goncalves A, Makalo P, Joof H, Burr S, Ramadhani A, Massae P, et al.
Hum Genet
. 2016 Jun;
135(8):939-51.
PMID: 27312142
NKG2C is an activating receptor that is preferentially expressed on natural killer (NK) cells. The gene encoding NKG2C (killer cell lectin-like receptor C2, KLRC2) is present at different copy numbers...
17.
Derrick T, Luthert P, Jama H, Hu V, Massae P, Essex D, et al.
PLoS Negl Trop Dis
. 2016 Jun;
10(6):e0004752.
PMID: 27249027
Purpose: To characterize the histological appearance and expression of pro-inflammatory mediators, growth factors, matrix metalloproteinases and biomarkers of epithelial-mesenchymal transition (EMT) in healthy control and trachomatous trichiasis (TT) conjunctival tissue....
18.
Hu V, Luthert P, Derrick T, Pullin J, Weiss H, Massae P, et al.
PLoS Negl Trop Dis
. 2016 May;
10(5):e0004734.
PMID: 27219121
Introduction: The phenotype and function of immune cells infiltrating the conjunctiva in scarring trachoma have yet to be fully characterized. We assessed tissue morphology and immunophenotype of cellular infiltrates found...
19.
Derrick T, Last A, Burr S, Roberts C, Nabicassa M, Cassama E, et al.
BMC Infect Dis
. 2016 Feb;
16:60.
PMID: 26842862
Background: Trachoma, a preventable blinding eye disease, is initiated by ocular infection with Chlamydia trachomatis (Ct). We previously showed that microRNAs (miR) -147b and miR-1285 were up-regulated in inflammatory trachomatous...
20.
Derrick T, Holland M, Cassama E, Markham-David R, Nabicassa M, Marks M, et al.
Parasit Vectors
. 2016 Jan;
9:30.
PMID: 26812948
Background: Trachoma is a blinding disease caused by conjunctival infection with Chlamydia trachomatis (Ct). Mass drug administration (MDA) for trachoma control is administered based on the population prevalence of the...