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Tamara L Wall

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Citations 3097
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Recent Articles
1.
Saunders G, Wang X, Chen F, Jang S, Liu M, Wang C, et al.
Nature . 2022 Dec; 612(7941):720-724. PMID: 36477530
Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of worldwide deaths, respectively, due largely to broad increased risk for disease and injury. These substances are used...
2.
Jami E, Hammerschlag A, Ip H, Allegrini A, Benyamin B, Border R, et al.
J Am Acad Child Adolesc Psychiatry . 2022 Apr; 61(7):934-945. PMID: 35378236
Objective: To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. Method: In 22 cohorts, multiple univariate genome-wide association studies (GWASs) were performed using repeated assessments of internalizing...
3.
Ip H, van der Laan C, Krapohl E, Brikell I, Sanchez-Mora C, Nolte I, et al.
Transl Psychiatry . 2021 Jul; 11(1):413. PMID: 34330890
Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages...
4.
McCabe C, Wall T, Gonzalez M, Meruelo A, Eberson-Shumate S, Clark D, et al.
Alcohol Clin Exp Res . 2021 May; 45(6):1249-1264. PMID: 33991389
Background: Dual systems theories suggest that greater imbalance between higher reward sensitivity and lower cognitive control across adolescence conveys risk for behaviors such as heavy episodic drinking (HED). Prior research...
5.
Johnson E, Demontis D, Thorgeirsson T, Walters R, Polimanti R, Hatoum A, et al.
Lancet Psychiatry . 2020 Oct; 7(12):1032-1045. PMID: 33096046
Background: Variation in liability to cannabis use disorder has a strong genetic component (estimated twin and family heritability about 50-70%) and is associated with negative outcomes, including increased risk of...
6.
Winiger E, Ellingson J, Morrison C, Corley R, Pasman J, Wall T, et al.
Sleep . 2020 Sep; 44(3). PMID: 32935850
Study Objectives: Estimate the genetic relationship of cannabis use with sleep deficits and an eveningness chronotype. Methods: We used linkage disequilibrium score regression (LDSC) to analyze genetic correlations between sleep...
7.
Ellingson J, Ross J, Winiger E, Stallings M, Corley R, Friedman N, et al.
Addiction . 2020 Sep; 116(4):833-844. PMID: 32881239
Aims: To examine whether moderate adolescent cannabis use has neurocognitive effects that are unexplained by familial confounds, which prior family-controlled studies may not have identified. Design: A quasi-experimental, sibling-comparison design...
8.
Polimanti R, Walters R, Johnson E, McClintick J, Adkins A, Adkins D, et al.
Mol Psychiatry . 2020 Feb; 25(8):1673-1687. PMID: 32099098
To provide insights into the biology of opioid dependence (OD) and opioid use (i.e., exposure, OE), we completed a genome-wide analysis comparing 4503 OD cases, 4173 opioid-exposed controls, and 32,500...
9.
Munn-Chernoff M, Johnson E, Chou Y, Coleman J, Thornton L, Walters R, et al.
Addict Biol . 2020 Feb; 26(1):e12880. PMID: 32064741
Eating disorders and substance use disorders frequently co-occur. Twin studies reveal shared genetic variance between liabilities to eating disorders and substance use, with the strongest associations between symptoms of bulimia...
10.
Wall T, Ehlers C
Alcohol Health Res World . 2019 Dec; 19(3):184-189. PMID: 31798054
Aldehyde dehydrogenase (ALDH) is one of the two enzymes primarily involved in alcohol metabolism. Several variants exist of the gene that produces ALDH. One of these gene variants, which generates...