Talia Velasco-Hernandez
Overview
Explore the profile of Talia Velasco-Hernandez including associated specialties, affiliations and a list of published articles.
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29
Citations
571
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Recent Articles
1.
Defective ribosome assembly impairs leukemia progression in a murine model of acute myeloid leukemia
Sjovall D, Ghosh S, Fernandez-Fuentes N, Velasco-Hernandez T, Hogmalm A, Menendez P, et al.
Cell Rep
. 2024 Oct;
43(11):114864.
PMID: 39412990
Despite an advanced understanding of disease mechanisms, the current therapeutic regimen fails to cure most patients with acute myeloid leukemia (AML). In the present study, we address the role of...
2.
Kodali S, Proietti L, Valcarcel G, Lopez-Rubio A, Pessina P, Eder T, et al.
Nat Cell Biol
. 2024 Aug;
26(10):1745-1758.
PMID: 39169219
Post-transcriptional mechanisms are fundamental safeguards of progenitor cell identity and are often dysregulated in cancer. Here, we identified regulators of P-bodies as crucial vulnerabilities in acute myeloid leukaemia (AML) through...
3.
Lopez-Millan B, Rubio-Gayarre A, Vinyoles M, Trincado J, Fraga M, Fernandez-Fuentes N, et al.
Blood
. 2024 Aug;
144(19):2002-2017.
PMID: 39093982
B-cell acute lymphoblastic leukemia (B-ALL) is the most common pediatric cancer, with long-term overall survival rates of ∼85%. However, B-ALL harboring rearrangements of the MLL gene (also known as KMT2A),...
4.
Bousquets-Munoz P, Molina O, Varela I, Alvarez-Eguiluz A, Fernandez-Mateos J, Gomez A, et al.
Leukemia
. 2024 May;
38(8):1808-1812.
PMID: 38806630
No abstract available.
5.
Velasco-Hernandez T, Trincado J, Vinyoles M, Closa A, Martinez-Moreno A, Gutierrez-Aguera F, et al.
Hemasphere
. 2024 Mar;
8(2):e45.
PMID: 38435427
Relapse remains a major challenge in the clinical management of acute myeloid leukemia (AML) and is driven by rare therapy-resistant leukemia stem cells (LSCs) that reside in specific bone marrow...
6.
Molina O, Ortega-Sabater C, Thampi N, Fernandez-Fuentes N, Guerrero-Murillo M, Martinez-Moreno A, et al.
EMBO Mol Med
. 2024 Jan;
16(1):64-92.
PMID: 38177531
Chromosomal instability (CIN) lies at the core of cancer development leading to aneuploidy, chromosomal copy-number heterogeneity (chr-CNH) and ultimately, unfavorable clinical outcomes. Despite its ubiquity in cancer, the presence of...
7.
Velasco-Hernandez T, Menendez P
Transl Pediatr
. 2023 Nov;
12(10):1913-1915.
PMID: 37969114
No abstract available.
8.
Bueno C, Torres-Ruiz R, Velasco-Hernandez T, Molina O, Petazzi P, Martinez A, et al.
Blood
. 2023 Sep;
142(20):1752-1756.
PMID: 37756522
Cellular ontogeny and MLL breakpoint site influence the capacity of MLL-edited CD34+ hematopoietic cells to initiate and recapitulate infant patients' features in pro-B-cell acute lymphoblastic leukemia (B-ALL). We provide key...
9.
Zhang Y, Velasco-Hernandez T, Mess J, Lalioti M, Romero-Mulero M, Obier N, et al.
Blood Adv
. 2023 Aug;
7(24):7525-7538.
PMID: 37639313
Leukemia stem cells (LSCs) share numerous features with healthy hematopoietic stem cells (HSCs). G-protein coupled receptor family C group 5 member C (GPRC5C) is a regulator of HSC dormancy. However,...
10.
Campos-Gonzalez G, Martinez-Picado J, Velasco-Hernandez T, Salgado M
Viruses
. 2023 Mar;
15(3).
PMID: 36992496
Chimeric antigen receptor (CAR) technology is having a huge impact in the blood malignancy field and is becoming a well-established therapy for many types of leukaemia. In recent decades, efforts...