Takuya Seike
Overview
Explore the profile of Takuya Seike including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
244
Followers
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Recent Articles
1.
Yamashima T, Mochly-Rosen D, Wakatsuki S, Mizukoshi E, Seike T, Larus I, et al.
Front Mol Biosci
. 2024 Jun;
11:1378656.
PMID: 38859931
Autophagy mediates the degradation of intracellular macromolecules and organelles within lysosomes. There are three types of autophagy: macroautophagy, microautophagy, and chaperone-mediated autophagy. Heat shock protein 70.1 (Hsp70.1) exhibits dual functions...
2.
Seike T, Chen C, Mochly-Rosen D
Front Aging Neurosci
. 2023 Sep;
15:1223977.
PMID: 37693648
Aldehyde dehydrogenase 2 (ALDH2) is an enzyme found in the mitochondrial matrix that plays a central role in alcohol and aldehyde metabolism. A common ALDH2 polymorphism in East Asians descent...
3.
Yamashima T, Seike T, Mochly-Rosen D, Chen C, Kikuchi M, Mizukoshi E
Front Aging Neurosci
. 2023 Sep;
15:1211141.
PMID: 37693644
Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme that reduces cell injuries via detoxification of lipid-peroxidation product, 4-hydroxy-2-nonenal (hydroxynonenal). It is generated exogenously via deep-frying of linoleic acid-rich cooking oils...
4.
Yamashima T, Mori Y, Seike T, Ahmed S, Boontem P, Li S, et al.
Nutrients
. 2023 Apr;
15(8).
PMID: 37111122
Hsp70.1 has a dual function as a chaperone protein and lysosomal stabilizer. In 2009, we reported that calpain-mediated cleavage of carbonylated Hsp70.1 causes neuronal death by inducing lysosomal rupture in...
5.
Yamashima T, Seike T, Oikawa S, Kobayashi H, Kido H, Yanagi M, et al.
Front Mol Biosci
. 2023 Feb;
9:1063632.
PMID: 36819480
Alzheimer's disease, type 2 diabetes, and non-alcoholic steatohepatitis (NASH) constitute increasingly prevalent disorders. Individuals with type 2 diabetes are well-known to be susceptible to Alzheimer's disease. Although the pathogenesis of...
6.
Fuchizaki U, Nagai K, Seike T
Gastroenterology
. 2022 Oct;
164(4):e1-e3.
PMID: 36195168
No abstract available.
7.
Fuchizaki U, Nagai K, Seike T
Gastroenterology
. 2022 Aug;
164(1):e10-e11.
PMID: 35964692
No abstract available.
8.
Seike T, Boontem P, Yanagi M, Li S, Kido H, Yamamiya D, et al.
Cell Mol Gastroenterol Hepatol
. 2022 Jul;
14(4):925-944.
PMID: 35787976
Background & Aims: The lipid oxidation is a key factor for damaging hepatocytes and causing cell death. However, the mechanisms underlying hepatocyte death and the role of the most popular...
9.
Hida Y, Kageji R, Bekku H, Watanabe S, Seike T, Yamashita M
Dermatol Online J
. 2022 May;
28(1).
PMID: 35499424
No abstract available.
10.