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Takeshi Osonoi

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Articles 74
Citations 913
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Recent Articles
1.
Sumida Y, Toyoda H, Yasuda S, Kimoto S, Sakamoto K, Nakade Y, et al.
J Atheroscler Thromb . 2024 May; 31(11):1620-1633. PMID: 38777770
Aim: No pharmacotherapeutic treatment has been established for metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH). This trial compared the effects of pemafibrate and omega-3-acid ethyl ester...
2.
Osonoi T, Oura T, Hirase T
Diabetes Obes Metab . 2023 Oct; 26(1):126-134. PMID: 37794628
Aim: To evaluate glycaemic control, body weight, and safety outcomes following treatment with tirzepatide or dulaglutide in patients with type 2 diabetes (T2D) with a baseline haemoglobin (HbA1c) level of...
3.
Mita T, Katakami N, Okada Y, Yoshii H, Osonoi T, Nishida K, et al.
Diabetologia . 2023 Sep; 66(12):2356-2367. PMID: 37750893
Aims/hypothesis: Previous studies have suggested that glucose variability may accelerate atherosclerosis progression in people with type 2 diabetes. Current guidelines recommend assessing glycaemic control using continuous glucose monitoring (CGM), which...
4.
Mita T, Katakami N, Yoshii H, Onuma T, Kaneto H, Osonoi T, et al.
Sci Rep . 2023 Sep; 13(1):14649. PMID: 37669959
We previously reported in the study of preventive effects of alogliptin on diabetic atherosclerosis (SPEAD-A) that alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, attenuated the progression of carotid atherosclerosis in subjects...
5.
Osonoi T, Shirabe S, Saito M, Hosoya M, Watahiki N, Douguchi S, et al.
Diabetes Metab Syndr Obes . 2023 Jun; 16:1799-1808. PMID: 37363130
Purpose: In this study, we examined the effects of dapagliflozin on changes in hematopoiesis, iron metabolism, and body composition indices in elderly type 2 diabetic patients with renal impairment and...
6.
Osonoi T, Shirabe S, Saito M, Hosoya M, Douguchi S, Ofuchi K, et al.
Front Pharmacol . 2023 Jun; 14:1205021. PMID: 37351507
Imeglimin is a novel type 2 diabetes (T2D) drug that is expected to improve mitochondrial function. In its phase 3 clinical trials in Japanese patients with T2D, the hemoglobin A1c...
7.
Katakami N, Mita T, Yoshii H, Shiraiwa T, Yasuda T, Okada Y, et al.
Cardiovasc Diabetol . 2023 Jun; 22(1):143. PMID: 37349722
Background: This study aimed to assess the long-term effects of tofogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes...
8.
Osonoi T, Saito M, Hosoya M, Douguchi S, Ofuchi K, Katoh M
Front Endocrinol (Lausanne) . 2023 Jan; 13:1042061. PMID: 36714585
Background: Dotinurad is a novel uricosuric drug in Japan with selective and potent urate transporter 1 (URAT1) inhibitory activity. This study aims to evaluate the efficacy and safety of dotinurad...
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Yoshii H, Mita T, Katakami N, Okada Y, Osonoi T, Aso K, et al.
J Clin Endocrinol Metab . 2022 Jul; 107(10):e3990-e4003. PMID: 35908248
Context: Current guidelines recommend assessing glycemic control using continuous glucose monitoring (CGM) and hemoglobin A1c (HbA1c) measurement. Objective: This study aimed to clarify the characteristics of patients who might benefit...