Takeshi Hiramoto
Overview
Explore the profile of Takeshi Hiramoto including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
442
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Recent Articles
11.
Hiramoto T, Kang G, Suzuki G, Satoh Y, Kucherlapati R, Watanabe Y, et al.
Hum Mol Genet
. 2011 Sep;
20(24):4775-85.
PMID: 21908517
Although twin studies indicate clear genetic bases of autism spectrum disorder (ASD), the precise mechanisms through which genetic variations causally result in ASD are poorly understood. Individuals with 3 Mb...
12.
Satoh Y, Endo S, Nakata T, Kobayashi Y, Yamada K, Ikeda T, et al.
J Neurosci
. 2011 Aug;
31(33):11953-67.
PMID: 21849556
Signaling through extracellular signal-regulated kinase (ERK) is important in multiple signal transduction networks in the CNS. However, the specific role of ERK2 in in vivo brain functions is not fully...
13.
Suzuki G, Harper K, Hiramoto T, Funke B, Lee M, Kang G, et al.
Hum Mol Genet
. 2009 Jul;
18(20):3914-25.
PMID: 19617637
Duplication of human chromosome 22q11.2 is associated with elevated rates of mental retardation, autism and many other behavioral phenotypes. However, because duplications cover 1.5-6 Mb, the precise manner in which...
14.
Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice
Suzuki G, Harper K, Hiramoto T, Sawamura T, Lee M, Kang G, et al.
Hum Mol Genet
. 2009 Feb;
18(9):1652-60.
PMID: 19240081
Deletion or duplication of the human chromosome 22q11.2 is associated with many behavioral traits and neuropsychiatric disorders, including autism spectrum disorders and schizophrenia. However, why phenotypes vary widely among individuals...
15.
Kikuchi A, Shimizu K, Nibuya M, Hiramoto T, Kanda Y, Tanaka T, et al.
Psychiatry Clin Neurosci
. 2008 Dec;
62(6):713-20.
PMID: 19068009
Aim: Inescapable shocks (IS) have been reported to reduce the number of 5-bromo-2'-deoxyuridine (BrdU)-positive cells in hippocampus. Antidepressants prevent this reduction, and the role of neurogenesis in depression is now...
16.
Hiramoto T, Satoh Y, Takishima K, Watanabe Y
Neuroreport
. 2008 May;
19(8):793-7.
PMID: 18446092
The radial migration is an important process in the development of the cerebral cortex. Earlier studies have reported that classical neurotransmitters such as L-dopamine and L-adrenaline regulate the proliferation of...
17.
Suzuki G, Kanda Y, Nibuya M, Hiramoto T, Tanaka T, Shimizu K, et al.
Brain Res
. 2007 Oct;
1183:21-31.
PMID: 17945200
GPR56, a member of the G-protein-coupled receptor family, plays a role in the formation of the frontal and parietal brain lobes and cortical lamination in the embryonic stage. A recent...
18.
Satoh Y, Endo S, Ikeda T, Yamada K, Ito M, Kuroki M, et al.
J Neurosci
. 2007 Oct;
27(40):10765-76.
PMID: 17913910
The extracellular signal-regulated kinase (ERK) 1 and 2 are important signaling components implicated in learning and memory. These isoforms display a high degree of sequence homology and share a similar...
19.
Hiramoto T, Kanda Y, Satoh Y, Takishima K, Watanabe Y
Neuroreport
. 2007 Apr;
18(7):659-64.
PMID: 17426594
We initially examined the effects of apomorphine in vitro using mouse embryonic and adult neural progenitor cells. The effects of apomorphine treatment led to dose-dependent increases in the number of...
20.
Hiramoto T, Ihara Y, Watanabe Y
Neurosci Lett
. 2006 Sep;
408(1):25-8.
PMID: 16989945
The proliferation of neural progenitor cells (NPCs) is regulated by classical neurotransmitters such as dopamine, serotonin and acetylcholine, via its own receptors. Previous studies have reported that the depletion of...