Takayuki Fujiwara
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Explore the profile of Takayuki Fujiwara including associated specialties, affiliations and a list of published articles.
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121
Citations
1329
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Recent Articles
1.
Fujiwara T, Ishii S, Minatsuki S, Hatano M, Takeda N
Int Heart J
. 2025 Feb;
66(1):3-12.
PMID: 39894550
Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by progressive obliteration of pulmonary arteries. Dysregulated bone morphogenetic protein (BMP) signaling pathway contributes to the development of PAH, and pulmonary...
2.
Yagisawa F, Fujiwara T, Yamashita S, Hirooka S, Tamashiro K, Izumi J, et al.
Plant Mol Biol
. 2024 Dec;
115(1):9.
PMID: 39699696
Inorganic polyphosphate (polyP) is a linear polymer of phosphate that plays various roles in cells, including in phosphate and metal homeostasis. Homologs of the vacuolar transporter chaperone 4 (VTC4), catalyzing...
3.
Togashi T, Baatartsogt N, Nagao Y, Kashiwakura Y, Hayakawa M, Hiramoto T, et al.
Arterioscler Thromb Vasc Biol
. 2024 Nov;
44(12):2616-2627.
PMID: 39508105
Background: PC (protein C) is a plasma anticoagulant encoded by ; mutation in both alleles results in neonatal purpura fulminans-a fatal systemic thrombotic disorder. In the present study, we aimed...
4.
Katoh M, Nomura S, Yamada S, Ito M, Hayashi H, Katagiri M, et al.
Circulation
. 2024 Jul;
150(5):374-389.
PMID: 38991046
Background: The heart comprises many types of cells such as cardiomyocytes, endothelial cells (ECs), fibroblasts, smooth muscle cells, pericytes, and blood cells. Every cell type responds to various stressors (eg,...
5.
Fujiwara T, Hirooka S, Yamashita S, Yagisawa F, Miyagishima S
Plant Physiol
. 2024 Jun;
196(1):77-94.
PMID: 38833589
An inducible protein-knockdown system is highly effective for investigating the functions of proteins and mechanisms essential for the survival and growth of organisms. However, this technique is not available in...
6.
Jimba T, Hatano M, Fujiwara T, Akazawa H, Watanabe M, Kinugawa K, et al.
J Cardiol Cases
. 2024 Jan;
29(1):7-10.
PMID: 38188322
Learning Objective: This report shows a progressive right ventricular failure (RVF) two years after left ventricular assist device (LVAD) implantation. Although the patient had no known risk factor, vicious circle...
7.
Ishii S, Fujiwara T, Yagi H, Takeda N, Ando M, Yamauchi H, et al.
Mol Genet Genomic Med
. 2023 Oct;
11(12):e2257.
PMID: 37864304
Objective: Loeys-Dietz syndrome (LDS) is a heritable disorder of connective tissue closely related to Marfan syndrome (MFS). LDS is caused by loss-of-function variants of genes that encode components of transforming...
8.
Hisanaga T, Romani F, Wu S, Kowar T, Wu Y, Lintermann R, et al.
Curr Biol
. 2023 Sep;
33(20):4367-4380.e9.
PMID: 37738971
The mobility of transposable elements (TEs) contributes to evolution of genomes. Their uncontrolled activity causes genomic instability; therefore, expression of TEs is silenced by host genomes. TEs are marked with...
9.
Fujiwara T, Takeda N, Hara H, Ishii S, Numata G, Tokiwa H, et al.
JCI Insight
. 2023 Sep;
8(17).
PMID: 37681410
Pulmonary hypertension (PH) is a life-threatening disease characterized by a progressive narrowing of pulmonary arterioles. Although VEGF is highly expressed in lung of patients with PH and in animal PH...
10.
Akashi N, Umemoto T, Yamada H, Fujiwara T, Yamamoto K, Taniguchi Y, et al.
Diabetes Metab Syndr Obes
. 2023 Apr;
16:1043-1054.
PMID: 37077576
Purpose: Dipeptidyl peptidase-4 (DPP-4) inhibitors increase endothelial progenitor cells (EPCs) in peripheral blood circulation. However, the underlying mechanisms and effects on vascular endothelial function remain unclear. We evaluated whether the...