Takashi Sakurai
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Explore the profile of Takashi Sakurai including associated specialties, affiliations and a list of published articles.
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372
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Recent Articles
11.
Murayama T, Otori Y, Kurebayashi N, Yamazawa T, Oyamada H, Sakurai T, et al.
Commun Biol
. 2024 Sep;
7(1):1108.
PMID: 39294299
The type 1 ryanodine receptor (RyR1) is a Ca release channel in the sarcoplasmic reticulum that is essential for skeletal muscle contraction. RyR1 forms a channel with six transmembrane segments,...
12.
Kinjo Y, Saji N, Murotani K, Sakima H, Takeda A, Sakurai T, et al.
J Alzheimers Dis
. 2024 Aug;
101(2):627-636.
PMID: 39213072
Background: Recent studies have demonstrated an association between pulse wave velocity (PWV), cerebral small vessel disease (SVD), and cognitive impairment such as Alzheimer's disease. However, the association between brachial-ankle PWV...
13.
Hori A, Inaba H, Hato T, Tanaka K, Sato S, Okamoto M, et al.
PLoS One
. 2024 Aug;
19(8):e0291887.
PMID: 39173065
Seizures are increasingly being recognized as the hallmark of Alzheimer's disease (AD). Neuronal hyperactivity can be a consequence of neuronal damage caused by abnormal amyloid β (Aß) depositions. However, it...
14.
Ikeda A, Meng H, Taniguchi D, Mio M, Funayama M, Nishioka K, et al.
PNAS Nexus
. 2024 Aug;
3(8):pgae319.
PMID: 39131911
CHCHD2 and CHCHD10, linked to Parkinson's disease and amyotrophic lateral sclerosis-frontotemporal dementia (ALS), respectively, are mitochondrial intermembrane proteins that form a heterodimer. This study aimed to investigate the impact of...
15.
Saji N, Kinjo Y, Murotani K, Niida S, Takeda A, Sakurai T
Sci Rep
. 2024 Jun;
14(1):13911.
PMID: 38886538
Previous studies have demonstrated associations between enlarged perivascular spaces (EPVS) and dementias such as Alzheimer's disease. However, an association between EPVS and dementia with Lewy bodies (DLB) has not yet...
16.
Fujisawa C, Umegaki H, Sugimoto T, Nakashima H, Komiya H, Watanabe K, et al.
Eur Geriatr Med
. 2024 Jun;
15(5):1503-1508.
PMID: 38877373
Purpose: To examine the extent to which patients with amnestic mild cognitive impairment (aMCI) or Alzheimer's disease (AD) perceive their own physical decline. Methods: This study included 4450 outpatients (1008...
17.
Yasuno F, Kimura Y, Ogata A, Ikenuma H, Abe J, Minami H, et al.
Brain Behav Immun Health
. 2024 May;
38:100795.
PMID: 38799793
Background: Positron emission tomography, which assesses the binding of translocator protein radiotracers, C-DPA-713, may be a sensitive method for determining glial-mediated neuroinflammation levels. This study investigated the relationship between regional...
18.
Uchida K, Sugimoto T, Murotani K, Tsujimoto M, Kishino Y, Kuroda Y, et al.
J Clin Psychiatry
. 2024 May;
85(2).
PMID: 38780537
To develop a combined index using cognitive function and instrumental activities of daily living (IADL) to discriminate between Clinical Dementia Rating (CDR) scores of 0.5 and 1 in the clinical...
19.
Sugimoto T, Saji N, Omura T, Tokuda H, Miura H, Kawashima S, et al.
Diabetes Obes Metab
. 2024 May;
26(8):3318-3327.
PMID: 38764360
Aim: To examine cross-sectional associations between continuous glucose monitoring (CGM)-derived metrics and cerebral small vessel disease (SVD) in older adults with type 2 diabetes. Materials And Methods: In total, 80...
20.
Sakurai T, Sugimoto T, Akatsu H, Doi T, Fujiwara Y, Hirakawa A, et al.
Alzheimers Dement
. 2024 Apr;
20(6):3918-3930.
PMID: 38646854
Introduction: We examined the efficacy of a multidomain intervention in preventing cognitive decline among Japanese older adults with mild cognitive impairment (MCI). Methods: Participants aged 65-85 years with MCI were...