Takashi Kamimura
Overview
Explore the profile of Takashi Kamimura including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
30
Citations
650
Followers
0
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Recent Articles
1.
Ichijo R, Kamimura T, Kawai G
Front Mol Biosci
. 2023 Mar;
10:1145528.
PMID: 36999159
RNA-targeted small molecules are a promising modality in drug discovery. Recently, we found that a fluoroquinolone derivative, KG022, can bind to RNAs with bulged C or G. To clarify the...
2.
Nagano K, Kamimura T, Kawai G
J Biochem
. 2021 Nov;
171(2):239-244.
PMID: 34791286
Interaction analysis between small molecules and RNA as well as structure determination of RNA-small molecule complexes will be the clues to search for compounds that bind to specific mRNA or...
3.
Fukushima K, Furuya M, Kamimura T, Takimoto-Kamimura M
Acta Crystallogr D Struct Biol
. 2021 Mar;
77(Pt 3):293-299.
PMID: 33645533
Methotrexate (MTX) is an anticancer and anti-rheumatoid arthritis drug that is considered to block nucleotide synthesis and the cell cycle mainly by inhibiting the activity of dihydrofolate reductase (DHFR). Using...
4.
Fukushima K, Kamimura T, Takimoto-Kamimura M
J Synchrotron Radiat
. 2013 Oct;
20(Pt 6):943-7.
PMID: 24121345
SLPI (secretory leukocyte protease inhibitor) is a 107-residue protease inhibitor which inhibits various serine proteases, including elastase, cathepsin G, chymotrypsin and trypsin. SLPI is obtained as a multiple inhibitor in...
5.
Muramatsu K, Niwa M, Nagai M, Kamimura T, Sasaki S, Ishiguro T
Neurosci Lett
. 2012 Nov;
531(2):109-13.
PMID: 23127853
Alterations in the number and size of motoneurons were studied in the medial gastrocnemius (MG) motor nucleus of diabetic rats (12 or 22 weeks after injection of storeptozotocin) and age-matched...
6.
Ochiai E, Kitagawa H, Takada I, Fujiyama S, Sawatsubashi S, Kim M, et al.
J Bone Miner Res
. 2009 Nov;
25(5):1157-66.
PMID: 19888899
Vitamin D plays an important role in regulating bone and calcium metabolism. The actions of vitamin D are mediated through the nuclear vitamin D receptor (VDR), and gene disruption of...
7.
Kamimura T, Yoshioka K, Ito S, Kusakabe T
Hum Mov Sci
. 2009 Apr;
28(4):407-14.
PMID: 19395107
The effects of isometric antagonist conditioning contraction (ACC) at various durations and intensities on the contractile force, electromyographic (EMG) amplitude, and their rates of rise of elbow flexor muscles were...
8.
Hirayama S, Ito T, Miyazaki O, Kamimura T, Hanyu O, Seino U, et al.
Clin Chim Acta
. 2008 Dec;
401(1-2):57-62.
PMID: 19056371
Background: Prebeta1-HDL is a minor HDL subfraction that is an initial acceptor of cellular free cholesterol. Prebeta1-HDL is elevated in hypertriglyceridemia, which is exaggerated with postprandial hyperglycemia. We investigated whether...
9.
Koizumi M, Fujino A, Fukushima K, Kamimura T, Takimoto-Kamimura M
J Synchrotron Radiat
. 2008 Apr;
15(Pt 3):308-11.
PMID: 18421166
SLPI (secretory leukocyte protease inhibitor) is a 107-residue non-glycosylated protease inhibitor, which inhibits a wide range of serine proteases, trypsin, chymotrypsin, neutrophil elastase, chymase and cathepsin G. X-ray crystallographic analyses...
10.
Ito M, Kodama M, Tsumanuma I, Ramadan M, Hirayama S, Kamimura T, et al.
Circ J
. 2007 Nov;
71(12):1955-7.
PMID: 18037753
Background: Increased cardiac insulin-like growth factor (IGF)-I production is associated with physiological cardiac hypertrophy in athletes, and IGF-I has been recognized as a cardioprotective agent in experimental animal studies. On...