Takashi Imai
Overview
Explore the profile of Takashi Imai including associated specialties, affiliations and a list of published articles.
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Articles
204
Citations
2569
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Recent Articles
1.
Doan V, Imai T, Kawazoe N, Chen G, Yoshitomi T
Acta Biomater
. 2025 Jan;
193:231-241.
PMID: 39788307
Tolerogenic dendritic cells with professional antigen presentation via major histocompatibility complex molecules, co-stimulatory molecules (CD80/86), and interleukin 10 production have attracted significant attention as cellular therapies for autoimmune, allergic, and...
2.
Doi K, Shinoto M, Isozaki T, Imai T, Aiba T, Hasegawa S, et al.
Anticancer Res
. 2024 Dec;
45(1):209-217.
PMID: 39740813
Background/aim: For patients with unresectable locally advanced pancreatic cancer (LAPC), carbon-ion radiotherapy (C-ion RT) can safely deliver higher doses than conventional photon therapy, increasing the potential for long-term survival. However,...
3.
Nakashima K, Imai T, Shiraishi A, Unose R, Goto H, Nagatomo Y, et al.
Clin Exp Immunol
. 2024 Jun;
217(3):291-299.
PMID: 38916251
The clinical spectrum of Down syndrome (DS) ranges from congenital malformations to premature aging and early-onset senescence. Excessive immunoreactivity and oxidative stress are thought to accelerate the pace of aging...
4.
Imai T, Lin J, Kaya G, Ju E, Kondylis V, Kelepouras K, et al.
Immunity
. 2024 May;
57(7):1497-1513.e6.
PMID: 38744293
RIPK1 is a multi-functional kinase that regulates cell death and inflammation and has been implicated in the pathogenesis of inflammatory diseases. RIPK1 acts in a kinase-dependent and kinase-independent manner to...
5.
Araki T, Koyama A, Yoshimura H, Arai A, Kawai S, Sekizawa S, et al.
Parasitol Int
. 2024 Mar;
101:102891.
PMID: 38537686
Malaria remains a significant global public health concern, with a recent increase in the number of zoonotic malaria cases in Southeast Asian countries. However, limited reports on the vector for...
6.
Horiuchi Y, Nakamura A, Imai T, Murakami T
PNAS Nexus
. 2024 Jan;
3(1):pgad484.
PMID: 38213616
Some properties of -infected cells overlap with immunogenic cell death. In this study, we demonstrated that intracellular infection of melanoma with induced high immunogenicity in melanoma cells, leading to antitumor...
7.
Tateishi Y, Araki T, Kawai S, Koide S, Umeki Y, Imai T, et al.
Parasitol Int
. 2024 Jan;
100:102856.
PMID: 38199522
The Plasmodium life cycle involves differentiation into multiple morphologically distinct forms, a process regulated by developmental stage-specific gene expression. Histone proteins are involved in epigenetic regulation in eukaryotes, and the...
8.
Mori A, Fujino S, Honda R, Kamijo K, Sano M, Imai T, et al.
Radiol Case Rep
. 2023 Nov;
19(1):141-145.
PMID: 37941983
Obstructed hemivagina and ipsilateral renal agenesis syndrome is a rare complex of structural abnormalities of female urogenital tract. Moreover, delayed treatment of this condition can reportedly lead to pelvic infection,...
9.
Imai T, Van T, Pasparakis M, Polykratis A
Sci Rep
. 2022 Jul;
12(1):12538.
PMID: 35869246
The development of atherosclerotic plaques is the result of a chronic inflammatory response coordinated by stromal and immune cellular components of the vascular wall. While endothelial cells and leukocytes are...
10.
Imai T, Ngo-Thanh H, Suzue K, Shimo A, Nakamura A, Horiuchi Y, et al.
Vaccines (Basel)
. 2022 May;
10(5).
PMID: 35632518
In our work, we aim to develop a malaria vaccine with cross-strain (-species) protection. C57BL/6 mice infected with the ANKA strain (PbA) develop experimental cerebral malaria (ECM). In contrast, ECM...