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Takako Enami

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Articles 18
Citations 91
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Recent Articles
1.
Suzuki H, Egawa N, Imamura K, Kondo T, Enami T, Tsukita K, et al.
Mol Brain . 2024 Mar; 17(1):14. PMID: 38444039
Synucleinopathies refer to a group of disorders characterized by SNCA/α-synuclein (α-Syn)-containing cytoplasmic inclusions and neuronal cell loss in the nervous system including the cortex, a common feature being cognitive impairment....
2.
Sawamura M, Imamura K, Hikawa R, Enami T, Nagahashi A, Yamakado H, et al.
Sci Rep . 2022 Jul; 12(1):12636. PMID: 35879519
Mutations within Superoxide dismutase 1 (SOD1) cause amyotrophic lateral sclerosis (ALS), accounting for approximately 20% of familial cases. The pathological feature is a loss of motor neurons with enhanced formation...
3.
Egawa N, Izumi Y, Suzuki H, Tsuge I, Fujita K, Shimano H, et al.
Sci Rep . 2022 May; 12(1):7988. PMID: 35568729
Dyslipidemia is considered an essential component of the pathological process of amyotrophic lateral sclerosis (ALS), a fatal motor neuron disease. Although TAR DNA Binding Protein 43 kDa (TDP-43) links both...
4.
Tan G, Kondo T, Imamura K, Suga M, Enami T, Nagahashi A, et al.
J Cell Mol Med . 2021 Sep; 25(20):9586-9596. PMID: 34510713
Human pluripotent stem cells have the potential to differentiate into various cell types including skeletal muscles (SkM), and they are applied to regenerative medicine or in vitro modelling for intractable...
5.
Yada Y, Suga M, Shibukawa R, Sagara Y, Okanishi Y, Enami T, et al.
Stem Cell Res . 2021 Aug; 55:102504. PMID: 34419750
Schizophrenia (SCZ) is one of the major psychiatric disorders. The genetic factor is certainly influential in the onset of the disease but is not decisive. There is no identified molecular/cellular...
6.
Imamura K, Sakurai Y, Enami T, Shibukawa R, Nishi Y, Ohta A, et al.
FEBS Open Bio . 2021 Apr; 11(5):1452-1464. PMID: 33822489
Human pathogenic RNA viruses are threats to public health because they are prone to escaping the human immune system through mutations of genomic RNA, thereby causing local outbreaks and global...
7.
Yada Y, Kondo T, Suga M, Tsukita K, Enami T, Shibukawa R, et al.
Stem Cell Res . 2021 Mar; 53:102274. PMID: 33714066
Idiopathic basal ganglia calcification (IBGC) is a rare neurodegenerative disease, characterized by abnormal calcium deposits in basal ganglia of the brain. The affected individuals exhibit movement disorders, and progressive deterioration...
8.
Imamura K, Yada Y, Izumi Y, Morita M, Kawata A, Arisato T, et al.
Ann Neurol . 2021 Feb; 89(6):1226-1233. PMID: 33565152
In amyotrophic lateral sclerosis (ALS), early diagnosis is essential for both current and potential treatments. To find a supportive approach for the diagnosis, we constructed an artificial intelligence-based prediction model...
9.
Suzuki H, Egawa N, Kondo T, Imamura K, Enami T, Tsukita K, et al.
Stem Cell Res . 2020 May; 45:101828. PMID: 32413791
Parkinson's disease (PD) is a devastating movement disorder with an unknown etiology. Multiplications of the SNCA gene cause the autosomal dominant form of familial PD as well as missense mutations...
10.
Takeuchi H, Imamura K, Ji B, Tsukita K, Enami T, Takao K, et al.
NPJ Vaccines . 2020 Mar; 5(1):28. PMID: 32219000
Pathological aggregates of tau proteins accumulate in the brains of neurodegenerative tauopathies including Alzheimer's disease and frontotemporal lobar degeneration (FTLD-tau). Although immunotherapies of these disorders against tau are emerging, it...