Takafumi Hamachi
Overview
Explore the profile of Takafumi Hamachi including associated specialties, affiliations and a list of published articles.
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11
Citations
195
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Recent Articles
1.
Takeshita M, Haraguchi A, Miura M, Hamachi T, Fukuda T, Sanui T, et al.
Clin Exp Dent Res
. 2018 May;
3(1):5-12.
PMID: 29744173
Mechanical reduction of infectious bacteria by using physical instruments is considered the principal therapeutic strategy for periodontal disease; addition of antibiotics is adjunctive. However, local antibiotic treatment, combined with conventional...
2.
Kitamura M, Akamatsu M, Kawanami M, Furuichi Y, Fujii T, Mori M, et al.
J Bone Miner Res
. 2015 Nov;
31(4):806-14.
PMID: 26547659
We investigated the efficacy, safety, and clinical significance of trafermin, a recombinant human fibroblast growth factor (rhFGF)-2, for periodontal regeneration in intrabony defects in Phase III trials. Study A, a...
3.
Matsuzaki E, Hiratsuka S, Hamachi T, Takahashi-Yanaga F, Hashimoto Y, Higashi K, et al.
Bone
. 2013 Apr;
55(2):315-24.
PMID: 23612487
Sphingosine-1-phosphate (S1P) is a well-known signaling sphingolipid and bioactive lipid mediator. Recently, it was reported that S1P inhibits osteoclast differentiation and bone resorption. On the other hand, S1P effects on...
4.
Kikuchi H, Fujise O, Miura M, Tanaka A, Hisano K, Haraguchi A, et al.
Microbiol Immunol
. 2012 Jul;
56(10):680-91.
PMID: 22812537
Above a critical concentration, amphiphilic lipopolysaccharide (LPS) molecules in an aqueous environment form aggregate structures, probably because of interactions involving hydrophobic bonds. Ionic bonds involving divalent cations stabilize these aggregate...
5.
Kitamura M, Nakashima K, Kowashi Y, Fujii T, Shimauchi H, Sasano T, et al.
PLoS One
. 2008 Jul;
3(7):e2611.
PMID: 18596969
Background: The options for medical use of signaling molecules as stimulators of tissue regeneration are currently limited. Preclinical evidence suggests that fibroblast growth factor (FGF)-2 can promote periodontal regeneration. This...
6.
Kaida H, Hamachi T, Anan H, Maeda K
J Endod
. 2007 Dec;
34(1):26-30.
PMID: 18155487
This study aimed to investigate the wound healing process of injured pulp tissues with Emdogain gel (EMD). Pulpotomy was performed for the first molars of the mandibles in rats. EMD...
7.
Fujise O, Miura M, Hamachi T, Maeda K
J Periodontol
. 2006 Aug;
77(8):1333-9.
PMID: 16881802
Background: Porphyromonas gingivalis is considered a critical pathogen of periodontal diseases including recurrent periodontitis. The profound effects of active periodontal treatment (APT) on P. gingivalis elimination were previously demonstrated and...
8.
Fujise O, Miura M, Hamachi T, Maeda K
J Periodontol
. 2005 Oct;
76(10):1661-6.
PMID: 16253087
Background: Porphyromonas gingivalis is considered a critical pathogen in periodontal diseases. It is classified into six genotypes based on diversity of the fimA gene encoding fimbrillin. The present study evaluated...
9.
Miura M, Hamachi T, Fujise O, Maeda K
J Periodontal Res
. 2005 Mar;
40(2):147-52.
PMID: 15733149
Background: The fimA gene, which encodes fimbrillin (FimA), is found in Porphyromonas gingivalis and has been classified into six genotypes based on nucleotide sequence. P. gingivalis that possesses the type...
10.
Yoneda M, Hirofuji T, Motooka N, Anan H, Hamachi T, Miura M, et al.
J Periodontal Res
. 2003 Nov;
38(6):551-6.
PMID: 14632916
Background: Porphyromonas gingivalis is one of the most important periodontopathogens. It produces cysteine proteinases named gingipains. We previously examined the effect of gingipains on abscess formation in a murine model....