Tahar van der Straaten
Overview
Explore the profile of Tahar van der Straaten including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
48
Citations
666
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Maagdenberg H, Bierings M, van Ommen C, van der Meer F, Appel I, Tamminga R, et al.
Pharmacogenomics
. 2018 Sep;
19(15):1195-1202.
PMID: 30207196
Aim: To study the effects of clinical and genetic factors on the phenprocoumon dose requirement in pediatric patients and to develop a dosing algorithm. Methods: Pediatric patients who used phenprocoumon...
2.
Verboom M, Kloth J, Swen J, der Straaten T, Bovee J, Sleijfer S, et al.
Eur J Cancer
. 2017 Oct;
86:226-232.
PMID: 29054076
Background: Imatinib 400 mg per day is first-line therapy for patients with gastrointestinal stromal tumours (GISTs). Although clinical benefit is high, progression-free survival (PFS) is variable. This study explores the...
3.
Lam S, van der Noort V, der Straaten T, Honkoop A, Peters G, Guchelaar H, et al.
Pharmacol Res
. 2017 Aug;
128:122-129.
PMID: 28827188
We examined whether genetic polymorphisms (SNPs) in the capecitabine activation pathway and CDA enzymatic activity were associated with prognosis, benefit from capecitabine-containing treatment or capecitabine-related toxicities. The study population comprised...
4.
Buermans H, Vossen R, Anvar S, Allard W, Guchelaar H, White S, et al.
Hum Mutat
. 2017 Jan;
38(3):310-316.
PMID: 28044414
Cytochrome P450 2D6 (CYP2D6) is among the most important genes involved in drug metabolism. Specific variants are associated with changes in the enzyme's amount and activity. Multiple technologies exist to...
5.
Zhang G, Guan Y, Zhao Y, der Straaten T, Xiao S, Xue P, et al.
Chem Biol Interact
. 2016 Dec;
263:55-65.
PMID: 28027876
Platinum-based treatment causes Pt-DNA adducts which lead to cell death. The platinum-induced DNA damage is recognized and repaired by the nucleotide excision repair (NER) system of which ERCC2/XPD is a...
6.
Xiao M, Xiao S, der Straaten T, Xue P, Zhang G, Zheng X, et al.
Mutat Res Genet Toxicol Environ Mutagen
. 2016 Dec;
812:39-47.
PMID: 27908386
Benzo[a]pyrene(B[a]P), and its ultimate metabolite Benzo[a]pyrene 7,8-diol 9,10-epoxide (BPDE), are classic DNA damaging carcinogens. DNA damage in cells caused by BPDE is normally repaired by Nucleotide Excision Repair (NER) and...
7.
Lam S, Frederiks C, der Straaten T, Honkoop A, Guchelaar H, Boven E
Br J Cancer
. 2016 Oct;
115(11):1335-1342.
PMID: 27736846
Background: The purpose of this study was to evaluate single-nucleotide polymorphisms (SNPs) in genes encoding key metabolising enzymes or involved in pharmacodynamics for possible associations with paclitaxel-induced peripheral neuropathy. Methods:...
8.
Moes D, Press R, Ackaert O, Ploeger B, Bemelman F, Diack C, et al.
Br J Clin Pharmacol
. 2016 Jun;
82(1):227-37.
PMID: 27334415
Aims: This study aimed at identifying pharmacological factors such as pharmacogenetics and drug exposure as new predictive biomarkers for delayed graft function (DGF), acute rejection (AR) and/or subclinical rejection (SCR)....
9.
Xiao S, Cui S, Lu X, Guan Y, Li D, Liu Q, et al.
Toxicol In Vitro
. 2016 May;
34:300-308.
PMID: 27139774
Nucleotide excision repair (NER) is an important defense mechanism of the body to exogenous carcinogens and mutagens, such as benzo[a]pyrene (B[a]P). Genetic polymorphisms in ERCC2/XPD, a critical element in NER,...
10.
de Groot S, Charehbili A, van Laarhoven H, Mooyaart A, Dekker-Ensink N, van de Ven S, et al.
Breast Cancer Res
. 2016 Jan;
18(1):3.
PMID: 26738606
Background: The insulin-like growth factor 1 (IGF-1) pathway is involved in cell growth and proliferation and is associated with tumorigenesis and therapy resistance. This study aims to elucidate whether variation...