Tae-Hong Kang
Overview
Explore the profile of Tae-Hong Kang including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
1146
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0
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Recent Articles
1.
Kang T
Int J Mol Sci
. 2023 Nov;
24(22).
PMID: 38003620
The intricate interplay between DNA damage response (DDR) and metabolism unveils a profound insight into the fundamental mechanisms governing the maintenance of genomic integrity [...].
2.
Jeon J, Lee S, Park J, Lee T, Kang T
Int J Biochem Cell Biol
. 2023 Aug;
162:106454.
PMID: 37574041
Cisplatin, a widely prescribed chemotherapeutic agent for treating solid tumors, induces DNA adducts and activates cellular defense mechanisms, including DNA repair, cell cycle checkpoint control, and apoptosis. Considering the circadian...
3.
Yi J, Kang T, Han Y, Park H, Yang J, Bae J, et al.
EMBO Rep
. 2023 Jun;
24(8):e56335.
PMID: 37341560
While there is growing evidence that many epigenetically silenced genes in cancer are tumour suppressor candidates, their significance in cancer biology remains unclear. Here, we identify human Neuralized (NEURL), which...
4.
Kang T
Biomolecules
. 2021 Jun;
11(5).
PMID: 34064641
Genomic integrity is constantly insulted by solar ultraviolet (UV) radiation. Adaptative cellular mechanisms called DNA damage responses comprising DNA repair, cell cycle checkpoint, and apoptosis, are believed to be evolved...
5.
Lee T, Choi J, Park J, Kang T
Oncogene
. 2020 Feb;
39(16):3245-3257.
PMID: 32086441
ATR and CHK1 play key roles in the protection and recovery of the stalled replication forks. Claspin, an adaptor for CHK1 activation, is essential for DNA damage signaling and efficient...
6.
Lee T, Kang T
Int J Mol Sci
. 2019 Dec;
20(23).
PMID: 31816862
The physiological impact of the aberrant oxidation products on genomic DNA were demonstrated by embryonic lethality or the cancer susceptibility and/or neurological symptoms of animal impaired in the base excision...
7.
Ha G, Ji J, Chae S, Park J, Kim S, Lee J, et al.
Nat Commun
. 2019 Apr;
10(1):1577.
PMID: 30952868
DNA double-strand break (DSB) signaling and repair are critical for genome integrity. They rely on highly coordinated processes including posttranslational modifications of proteins. Here we show that Pellino1 (Peli1) is...
8.
Park J, Lee T, Kang T
Int J Mol Sci
. 2018 Nov;
19(11).
PMID: 30380668
Genetic loss or mutations in tumor suppressor genes promote tumorigenesis. The prospective tumor suppressor tristetraprolin (TTP) has been shown to negatively regulate tumorigenesis through destabilizing the messenger RNAs of critical...
9.
Park J, Kang T
Int J Mol Sci
. 2016 Nov;
17(11).
PMID: 27827925
Ultraviolet (UV) radiation from sunlight represents a constant threat to genome stability by generating modified DNA bases such as cyclobutane pyrimidine dimers (CPD) and pyrimidine-pyrimidone (6-4) photoproducts (6-4PP). If unrepaired,...
10.
Lee J, Park J, Kang T
BMB Rep
. 2016 Jul;
49(10):566-571.
PMID: 27470212
Forskolin (FSK), an adenylyl cyclase activator, has recently been shown to enhance nucleotide excision repair (NER) upon UV exposure. However, our study revealed that this effect was detected in human...