Tae-Cheon Kang
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Explore the profile of Tae-Cheon Kang including associated specialties, affiliations and a list of published articles.
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256
Citations
5228
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Recent Articles
1.
Kim J, Lee D, Wang S, Kang T
Mol Cell Neurosci
. 2025 Mar;
133:103995.
PMID: 40032027
Glutathione (GSH) and heat shock protein 25 (HSP25) reciprocally regulate each other, which maintain redox homeostasis. Since P2X7 receptor (P2X7R) regulates GSH biosynthesis and HSP25 induction, the present study was...
2.
Kim J, Wang S, Lee D, Kim T, Kang T
Brain Res
. 2024 Nov;
1849():149345.
PMID: 39581524
Recently, we have reported that pyridoxal-5'-phosphate phosphatase/chronophin (PLPP/CIN) selectively dephosphorylates neurofibromin 2 (NF2, also known as merlin) at serine (S) 10 site. Since NF2 inhibits p21-activated kinase 1 (PAK1)-mediated nuclear...
3.
Wang S, Lee D, Kim T, Kim J, Kang T
Cell Death Dis
. 2024 Sep;
15(9):707.
PMID: 39349423
Loss of parvalbumin (PV) expressing neurons (PV neurons) is relevant to the underlying mechanisms of the pathogenesis of neurological and psychiatric diseases associated with the dysregulation of neuronal excitatory networks...
4.
Kim J, Lee D, Wang S, Kim T, Kang T
Neuropharmacology
. 2024 Aug;
260:110135.
PMID: 39214451
Glutathione peroxidase-1 (GPx1) and cAMP/Ca responsive element (CRE)-binding protein (CREB) regulate neuronal viability by maintaining the redox homeostasis. Since GPx1 and CREB reciprocally regulate each other, it is likely that...
5.
Kim J, Lee D, Kim T, Park H, Kang T
Antioxidants (Basel)
. 2023 May;
12(5).
PMID: 37237886
The downregulation of glutathione peroxidase-1 (GPx1) plays a role in clasmatodendrosis (an autophagic astroglial death) in the hippocampus of chronic epilepsy rats. Furthermore, N-acetylcysteine (NAC, a GSH precursor) restores GPx1...
6.
Kim J, Lee D, Kim T, Park H, Kim M, Kang T
J Neuroinflammation
. 2023 Apr;
20(1):99.
PMID: 37118736
Background: Pyridoxal-5'-phosphate phosphatase/chronophin (PLPP/CIN) selectively dephosphorylates serine (S) 10 site on neurofibromin 2 (NF2, also known as merlin (moesin-ezrin-radixin-like protein) or schwannomin). p21-activated kinase 1 (PAK1) is a serine/threonine protein...
7.
Kim J, Lee D, Kang T
Antioxidants (Basel)
. 2023 Apr;
12(4).
PMID: 37107345
Status epilepticus (SE) evokes leukocyte infiltration in the frontoparietal cortex (FPC) without the blood-brain barrier disruption. Monocyte chemotactic protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2) regulate leukocyte recruitments into the...
8.
Kim J, Kim T, Kang T
Antioxidants (Basel)
. 2023 Apr;
12(4).
PMID: 37107343
Epigallocatechin-3-gallate (EGCG) is an antioxidant that directly scavenges reactive oxygen species (ROS) and inhibits pro-oxidant enzymes. Although EGCG protects hippocampal neurons from status epilepticus (SE, a prolonged seizure activity), the...
9.
Lee D, Kim T, Park H, Kang T
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982567
andem of P domains in a weak inwardly rectifying K channel (TWIK)-related cid ensitive -1 channel (TASK-1) is activated under extracellular alkaline conditions (pH 7.2-8.2), which are upregulated in astrocytes...
10.
Kim J, Lee D, Kim T, Park H, Kim M, Kang T
Neuropharmacology
. 2023 Feb;
228:109462.
PMID: 36792029
Dopamine plays a central role in the regulation of psychomotor functions in the brain. Furthermore, the dopaminergic system is involved in the ictogenesis in human patients and animal models of...