Tadashi Sasagawa
Overview
Explore the profile of Tadashi Sasagawa including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
374
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0
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Recent Articles
1.
Sasagawa T, Nagamatsu T, Shibuya M
Exp Cell Res
. 2023 Jan;
424(1):113500.
PMID: 36720378
The Fms-like tyrosine kinase-1 (FLT1) gene is expressed in various types of cells, including vascular endothelial cells and placental trophoblasts, and regulates angiogenesis, inflammation, and pregnancy. However, the basal transcriptional...
2.
Sasagawa T, Nagamatsu T, Yanagisawa M, Fujii T, Shibuya M
Mol Hum Reprod
. 2021 Oct;
27(12).
PMID: 34665260
Placental hypoxia and increased levels of maternal blood anti-angiogenic protein, soluble fms-like tyrosine kinase-1 (sFLT1), are associated with the pathogenesis of pre-eclampsia. We have demonstrated that hypoxia-inducible factor (HIF)-2α mediates...
3.
Shibuya M, Matsui H, Sasagawa T, Nagamatsu T
Sci Rep
. 2021 Oct;
11(1):20613.
PMID: 34663835
In normal pregnancy, the soluble form of FMS-like tyrosine kinase-1 (sFLT1)/ vascular endothelial growth factor receptor-1 (sVEGFR-1), a VEGF-trapping protein, is expressed in trophoblasts of the placenta, suggesting that it...
4.
Sasagawa T, Jinno-Oue A, Nagamatsu T, Morita K, Tsuruga T, Mori-Uchino M, et al.
BMC Cancer
. 2020 Feb;
20(1):112.
PMID: 32041578
Background: Soluble Fms-like tyrosine kinase-1 (sFLT1) as an anti-angiogenic factor is abundantly expressed in placental trophoblasts. Choriocarcinoma, a malignant tumor derived from trophoblasts, is known to be highly angiogenic and...
5.
Sasagawa T, Nagamatsu T, Morita K, Mimura N, Iriyama T, Fujii T, et al.
Sci Rep
. 2018 Nov;
8(1):17375.
PMID: 30478339
Placental hypoxia and elevated levels of circulating soluble Fms-like tyrosine kinase-1 (sFlt-1), an anti-angiogenic factor, are closely related to the pathogenesis of preeclampsia. Although sFlt-1 secretion from the placental trophoblasts...
6.
Sasagawa T, Shimizu T, Yamato M, Okano T
J Tissue Eng Regen Med
. 2014 Mar;
10(9):739-47.
PMID: 24668945
Vascular-derived endothelial cell (EC) network prefabrication in three-dimensional (3D) tissue constructs before transplantation is useful for inducing functional anastomosis with the host vasculature. However, the clinical application of ECs is...
7.
Sasagawa T, Shimizu T, Yamato M, Okano T
Biomaterials
. 2013 Oct;
35(1):206-13.
PMID: 24119455
The prefabrication of endothelial cell network assembly (ECNA) in tissue-engineer multi-layered cell-sheets, known as in vitro prevascularization, is beneficial strategy for inducing anastomosis with the host vasculature after transplantation. However,...
8.
Sasagawa T, Shimizu T, Sekiya S, Yamato M, Okano T
J Biomed Mater Res A
. 2013 Mar;
102(2):358-65.
PMID: 23533096
Layered adipose-derived stem cell (ADSC) sheet transplantation is attracting attention as a new stem cell therapeutic strategy for damaged hearts. To prolong the function of tissue-engineered constructs after transplantation, a...
9.
Haraguchi Y, Shimizu T, Sasagawa T, Sekine H, Sakaguchi K, Kikuchi T, et al.
Nat Protoc
. 2012 Apr;
7(5):850-8.
PMID: 22481530
The fabrication of 3D tissues retaining the original functions of tissues/organs in vitro is crucial for optimal tissue engineering and regenerative medicine. The fabrication of 3D tissues also contributes to...
10.
Sekiya S, Muraoka M, Sasagawa T, Shimizu T, Yamato M, Okano T
Microvasc Res
. 2010 Aug;
80(3):549-51.
PMID: 20696176
Angiogenesis is a complicated natural process, and understanding the mechanism by which it occurs is important for medical, pharmaceutical, and cell biological sciences. Many techniques for investigating angiogenesis have been...