Tabea Erdmann
Overview
Explore the profile of Tabea Erdmann including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
418
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0
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Recent Articles
1.
Juilland M, Alouche N, Ubezzi I, Gonzalez M, Rashid H, Scarpellino L, et al.
Proc Natl Acad Sci U S A
. 2023 Dec;
120(52):e2301155120.
PMID: 38109544
The protease MALT1 promotes lymphocyte activation and lymphomagenesis by cleaving a limited set of cellular substrates, most of which control gene expression. Here, we identified the integrin-binding scaffold protein Tensin-3...
2.
Frontzek F, Staiger A, Wullenkord R, Grau M, Zapukhlyak M, Kurz K, et al.
Leukemia
. 2023 Jan;
37(3):670-679.
PMID: 36604606
Epstein-Barr virus (EBV) associated diffuse large B-cell lymphoma (DLBCL) represents a rare aggressive B-cell lymphoma subtype characterized by an adverse clinical outcome. EBV infection of lymphoma cells has been associated...
3.
Xu W, Berning P, Erdmann T, Grau M, Bettazova N, Zapukhlyak M, et al.
Leukemia
. 2022 Nov;
37(1):178-189.
PMID: 36352190
Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease that exhibits constitutive activation of phosphoinositide 3-kinase (PI3K) driven by chronic B-cell receptor signaling or PTEN deficiency. Since pan-PI3K inhibitors cause...
4.
Burkhardt B, Michgehl U, Rohde J, Erdmann T, Berning P, Reutter K, et al.
Nat Commun
. 2022 Jul;
13(1):3881.
PMID: 35794096
While survival has improved for Burkitt lymphoma patients, potential differences in outcome between pediatric and adult patients remain unclear. In both age groups, survival remains poor at relapse. Therefore, we...
5.
Frontzek F, Staiger A, Zapukhlyak M, Xu W, Bonzheim I, Borgmann V, et al.
Nat Commun
. 2021 Sep;
12(1):5183.
PMID: 34465776
Plasmablastic lymphoma (PBL) represents a rare and aggressive lymphoma subtype frequently associated with immunosuppression. Clinically, patients with PBL are characterized by poor outcome. The current understanding of the molecular pathogenesis...
6.
McDonald G, Chubukov V, Coco J, Truskowski K, Narayanaswamy R, Choe S, et al.
Mol Cancer Ther
. 2020 Oct;
19(12):2502-2515.
PMID: 33082276
Agents targeting metabolic pathways form the backbone of standard oncology treatments, though a better understanding of differential metabolic dependencies could instruct more rationale-based therapeutic approaches. We performed a chemical biology...
7.
Bucher P, Erdmann T, Grondona P, Xu W, Schmitt A, Schurch C, et al.
Blood
. 2019 Dec;
135(2):121-132.
PMID: 31794606
Diffuse large B-cell lymphoma (DLBCL) represents the most common adult lymphoma and can be divided into 2 major molecular subtypes: the germinal center B-cell-like and the aggressive activated B-cell-like (ABC)...
8.
Gehring T, Erdmann T, Rahm M, Grass C, Flatley A, ONeill T, et al.
Cell Rep
. 2019 Oct;
29(4):873-888.e10.
PMID: 31644910
The CARMA1/CARD11-BCL10-MALT1 (CBM) complex bridges T and B cell antigen receptor (TCR/BCR) ligation to MALT1 protease activation and canonical nuclear factor κB (NF-κB) signaling. Using unbiased mass spectrometry, we discover...
9.
Wullenkord R, Friedrichs B, Erdmann T, Lenz G
Expert Rev Hematol
. 2019 Oct;
12(12):1053-1062.
PMID: 31583927
: Aberrant phosphatidylinositide 3-kinase (PI3K) signaling drives survival and proliferation of malignant B-cells of different lymphoma entities. Thus, inhibition of PI3K isoforms represents a novel and promising therapeutic approach for...
10.
Fischer J, Walter C, Tonges A, Aleth H, Jordao M, Leddin M, et al.
Nat Immunol
. 2019 Mar;
20(5):546-558.
PMID: 30911105
Neutrophils are essential first-line defense cells against invading pathogens, yet when inappropriately activated, their strong immune response can cause collateral tissue damage and contributes to immunological diseases. However, whether neutrophils...