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T Shinnick

Explore the profile of T Shinnick including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
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Recent Articles
11.
Hasan A, Fortune F, Wilson A, Warr K, Shinnick T, Mizushima Y, et al.
Lancet . 1996 Mar; 347(9004):789-94. PMID: 8622334
Background: Behcet's disease (BD) is a multisystem disorder of unknown pathogenesis. The diagnosis is based on a set of international clinical criteria. Previous investigations have suggested that immunological cross-reactivity between...
12.
McNicholl J, Whitworth W, Oftung F, Fu X, Shinnick T, Jensen P, et al.
J Immunol . 1995 Aug; 155(4):1951-63. PMID: 7636246
We identified functionally important regions of the DR(alpha, beta 1*0401) peptide binding site and present a model of bound peptide. DR(alpha, beta 1*0401)-restricted T cell recognition and peptide binding of...
13.
Hasan A, Childerstone A, Pervin K, Shinnick T, Mizushima Y, van der Zee R, et al.
Clin Exp Immunol . 1995 Mar; 99(3):392-7. PMID: 7533679
T cell epitopes of the 65-kD heat shock protein (hsp) were investigated in patients with recurrent oral ulcers (ROU). Peripheral blood mononuclear cells were stimulated with overlapping synthetic peptide (15ers),...
14.
Stanford M, Kasp E, Whiston R, Hasan A, Todryk S, Shinnick T, et al.
Clin Exp Immunol . 1994 Aug; 97(2):226-31. PMID: 7519530
Mycobacterial and homologous human heat shock protein T cell peptide epitopes specific for T lymphocytes in Behçet's disease were investigated for their pathogenicity in Lewis rats. The potential pathogenicity of...
15.
Noordhoek G, Kolk A, Bjune G, Catty D, Dale J, Fine P, et al.
J Clin Microbiol . 1994 Feb; 32(2):277-84. PMID: 8150935
PCR is, in principle, a simple and rapid test for use in the detection of Mycobacterium tuberculosis. However, virtually no data are available on the reliability and reproducibility of the...
16.
Pervin K, Childerstone A, Shinnick T, Mizushima Y, van der Zee R, Hasan A, et al.
J Immunol . 1993 Aug; 151(4):2273-82. PMID: 7688396
T cell epitopes of the 65-kDa heat shock protein (HSP) were mapped in patients with Behçet's disease (BD), by stimulating T cells with the overlapping synthetic peptides derived from the...
17.
Nolte F, Metchock B, McGowan Jr J, Edwards A, Okwumabua O, Thurmond C, et al.
J Clin Microbiol . 1993 Jul; 31(7):1777-82. PMID: 8349753
A polymerase chain reaction (PCR) assay for the rapid diagnosis of pulmonary tuberculosis was developed by using oligonucleotide primers to amplify a fragment of IS6110, an insertion sequence repeated multiple...
18.
Quayle A, Wilson K, Li S, Kjeldsen-Kragh J, Oftung F, Shinnick T, et al.
Eur J Immunol . 1992 May; 22(5):1315-22. PMID: 1577070
A commonly held postulate regarding the etiology of rheumatoid arthritis (RA) is that of antigenic mimicry. Recent interest has focused on the mycobacterial 65-kDa heat-shock protein (hsp) as a putative...
19.
Lehner T, Lavery E, Smith R, van der Zee R, Mizushima Y, Shinnick T
Infect Immun . 1991 Apr; 59(4):1434-41. PMID: 2004821
The etiology of Behcet's syndrome (BS) is unknown, but a number of streptococcal species have been implicated. A hypothesis was postulated that a shared antigen, such as a stress protein,...
20.
Born W, Hall L, Dallas A, Boymel J, Shinnick T, Young D, et al.
Science . 1990 Jul; 249(4964):67-9. PMID: 1695022
Small synthetic peptides that correspond to different portions of the 65-kilodalton mycobacterial heat shock protein (Hsp65) were used to identify a putative antigenic epitope for gamma delta cells. Weaker gamma...