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T S Mikkelsen

Explore the profile of T S Mikkelsen including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 798
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Recent Articles
1.
Persky N, Hernandez D, Do Carmo M, Brenan L, Cohen O, Kitajima S, et al.
Nat Struct Mol Biol . 2020 Jan; 27(1):92-104. PMID: 31925410
Kinases are involved in disease development and modulation of their activity can be therapeutically beneficial. Drug-resistant mutant kinases are valuable tools in drug discovery efforts, but the prediction of mutants...
2.
Lancaster C, Bruun G, Peer C, Mikkelsen T, Corydon T, Gibson A, et al.
Clin Pharmacol Ther . 2012 Sep; 92(5):642-50. PMID: 22990751
Previous studies have demonstrated that the pharmacokinetic profile of erythromycin, a probe for CYP3A4 activity, is affected by inhibitors or inducers of hepatic solute carriers. We hypothesized that these interactions...
3.
Filipski K, Mathijssen R, Mikkelsen T, Schinkel A, Sparreboom A
Clin Pharmacol Ther . 2009 Jul; 86(4):396-402. PMID: 19625999
Cisplatin is one of the most widely used anticancer agents for the treatment of solid tumors. The clinical use of cisplatin is associated with dose-limiting nephrotoxicity, which occurs in one-third...
4.
Sabeti P, Schaffner S, Fry B, Lohmueller J, Varilly P, Shamovsky O, et al.
Science . 2006 Jun; 312(5780):1614-20. PMID: 16778047
Positive natural selection is the force that drives the increase in prevalence of advantageous traits, and it has played a central role in our development as a species. Until recently,...
5.
Mikkelsen T, Toft P
Acta Anaesthesiol Scand . 2005 Jun; 49(6):859-64. PMID: 15954972
Background: (I) To investigate the kinetics of the myoglobin and creatine kinase (CK) in rhabdomyolysis. Especially to describe those patients in whom an isolated increase in the myoglobin or the...