T R Caulfield
Overview
Explore the profile of T R Caulfield including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
68
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0
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Recent Articles
1.
Paulus A, Akhtar S, Yousaf H, Manna A, Paulus S, Bashir Y, et al.
Blood Cancer J
. 2017 May;
7(5):e565.
PMID: 28548645
Although ibrutinib is highly effective in Waldenstrom macroglobulinemia (WM), no complete remissions in WM patients treated with ibrutinib have been reported to date. Moreover, ibrutinib-resistant disease is being steadily reported...
2.
Paulus A, Akhtar S, Caulfield T, Samuel K, Yousaf H, Bashir Y, et al.
Blood Cancer J
. 2016 Nov;
6(11):e492.
PMID: 27813535
The survival of Waldenstrom macroglobulinemia (WM) tumor cells hinges on aberrant B-cell receptor (BCR) and MYD88 signaling. WM cells upregulate the proteasome function to sustain the BCR-driven growth while maintaining...
3.
Nimbolide targets BCL2 and induces apoptosis in preclinical models of Waldenströms macroglobulinemia
Chitta K, Paulus A, Caulfield T, Akhtar S, Blake M, Ailawadhi S, et al.
Blood Cancer J
. 2014 Nov;
4:e260.
PMID: 25382610
Neem leaf extract (NLE) has medicinal properties, which have been attributed to its limonoid content. We identified the NLE tetranorterpenoid, nimbolide, as being the key limonoid responsible for the cytotoxicity...